To PEGylate or not to PEGylate: Immunological properties of nanomedicine's most popular component, polyethylene glycol and its alternatives
Polyethylene glycol or PEG has a long history of use in medicine. Many conventional
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …
Bioengineered nanogels for cancer immunotherapy
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
Polyphenol‐containing nanoparticles: synthesis, properties, and therapeutic delivery
Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in
natural plants and have shown beneficial effects on human health. Recently, polyphenol …
natural plants and have shown beneficial effects on human health. Recently, polyphenol …
The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics
The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
Biomedical polymers: synthesis, properties, and applications
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
Nanogels: Synthesis, properties, and recent biomedical applications
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
DNA nanotechnology-enabled drug delivery systems
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
Biomineralized metal–organic framework nanoparticles enable intracellular delivery and endo-lysosomal release of native active proteins
TT Chen, JT Yi, YY Zhao, X Chu - Journal of the American …, 2018 - ACS Publications
Efficient delivery and endo-lysosomal release of active proteins in living cells remain a
challenge in protein-based theranostics. We report a novel protein delivery platform using …
challenge in protein-based theranostics. We report a novel protein delivery platform using …
Nanotechnology: a new opportunity in plant sciences
The agronomic application of nanotechnology in plants (phytonanotechnology) has the
potential to alter conventional plant production systems, allowing for the controlled release …
potential to alter conventional plant production systems, allowing for the controlled release …