The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Numerous studies have documented increases in matrix metalloproteinases (MMPs),
specifically MMP-9 levels following stroke, with such perturbations associated with …

Matrix metalloproteinases (MMPs) are a group of over twenty proteases, operating chiefly
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …

Matrix metalloproteinases are versatile endopeptidases with many different functions in the
body in health and disease. In the brain, matrix metalloproteinases are critical for tissue …

The matrix metalloproteinases (MMPs) form an enzyme family of which gelatinase B (MMP-
9) represents the largest and most complex member. We focus here on the biochemical …

The nature of microglia fascinated many prominent researchers in the 19th and early 20th
centuries, and in a classic treatise in 1932, Pio del Rio-Hortega formulated a number of …

Matrix metalloproteinases (MMPs) have been implicated in several diseases of the nervous
system. Here we review the evidence that supports this idea and discuss the possible …

Matrix metalloproteinases (MMPs) are a gene family of neutral proteases that are important
in normal development, wound healing, and a wide variety of pathological processes …

Background and Purpose—An abnormal expression of some matrix metalloproteinases
(MMPs) is related with hemorrhagic transformation events after stroke. Our aim was to …

Vascular cognitive impairment and dementia (VCID) include a wide spectrum of chronic
manifestations of vascular disease related to large vessel strokes and small vessel disease …