Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

The treatment of spinal cord injury (SCI) remains unsatisfactory owing to the complex
pathophysiological microenvironments at the injury site and the limited regenerative …

Osteoarthritis (OA) is a chronic joint disease characterized by progressive degeneration of
articular cartilage. A challenge in the development of disease-modifying drugs is effective …

Macrophage polarization determines the production of cytokines that fuel the initiation and
evolution of rheumatoid arthritis (RA). Thus, modulation of macrophage polarization might …

Spinal cord injury (SCI) can lead to iron overloading and subsequent neuronal ferroptosis,
which hinders the recovery of locomotor function. However, it is still unclear whether the …

Following ischemic stroke, brain‐resident activated microglia and peripherally infiltrated
inflammatory cells create a complicated and overactivated brain immune microenvironment …

Rheumatoid arthritis (RA) is the most prevalent inflammatory joint disease worldwide,
leading to irreversible disability and even mortality. Unfortunately, current treatment …

Scavenging free radicals and reducing inflammatory reaction to relieve the secondary
damage are important issues in the spinal cord injury (SCI) therapeutic strategy. Nanozymes …

Intervertebral disc degeneration (IVDD) is commonly caused by imbalanced oxygen
metabolism-triggered inflammation. Overcoming the shortcomings of antioxidants in IVDD …