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Toward Microbiome Engineering: expanding the repertoire of genetically tractable members of the human gut Microbiome
Genetic manipulation is necessary to interrogate the functions of microbes in their
environments, such as the human gut microbiome. Yet, the vast majority of human gut …
environments, such as the human gut microbiome. Yet, the vast majority of human gut …
Systems and synthetic biology-driven engineering of live bacterial therapeutics
The past decade has seen growing interest in bacterial engineering for therapeutically
relevant applications. While early efforts focused on repurposing genetically tractable model …
relevant applications. While early efforts focused on repurposing genetically tractable model …
Advances in synthetic biology toolboxes paving the way for mechanistic understanding and strain engineering of gut commensal Bacteroides spp. and Clostridium spp …
The gut microbiota plays a significant role in influencing human immunity, metabolism,
development, and behavior by producing a wide range of metabolites. While there is …
development, and behavior by producing a wide range of metabolites. While there is …
Engineering Microbial Consortia as Living Materials: Advances and Prospectives
The field of Engineered Living Materials (ELMs) integrates engineered living organisms into
natural biomaterials to achieve diverse objectives. Multiorganism consortia, prevalent in …
natural biomaterials to achieve diverse objectives. Multiorganism consortia, prevalent in …
[HTML][HTML] Genome engineering of the human gut microbiome
The human gut microbiome, a complex ecosystem, significantly influences host health,
impacting crucial aspects such as metabolism and immunity. To enhance our …
impacting crucial aspects such as metabolism and immunity. To enhance our …
[HTML][HTML] The most promising next-generation probiotic candidates—impact on Human Health and potential application in Food Technology
P Lalowski, D Zielińska - Fermentation, 2024 - mdpi.com
A substantial body of research indicates that the gut microbiota exerts a profound influence
on host health. The purpose of this work was to characterize selected, most promising, well …
on host health. The purpose of this work was to characterize selected, most promising, well …
Advancements in gene editing technologies for probiotic-enabled disease therapy
L Wang, J Hu, K Li, Y Zhao, M Zhu - Iscience, 2024 - cell.com
Probiotics typically refer to microorganisms that have been identified for their health benefits,
and they are added to foods or supplements to promote the health of the host. A growing …
and they are added to foods or supplements to promote the health of the host. A growing …
[HTML][HTML] EcoGenoRisk: Develo** a computational ecological risk assessment tool for synthetic biology
The expanding field of synthetic biology (synbio) supports new opportunities in the design of
targeted bioproducts or modified microorganisms. However, this rapid development of …
targeted bioproducts or modified microorganisms. However, this rapid development of …
A Nitrate/Nitrite Biosensor Designed with an Antiterminator for In Vivo Diagnosis of Colitis Based on Bacteroides thetaiotaomicron
X Yang, M Ye, F Wang, X Yang, X Gao, J Yu… - ACS Synthetic …, 2025 - ACS Publications
Bacteroides thetaiotaomicron is a common microorganism in the human gut that has been
linked to health benefits. Furthermore, it is an emerging synthetic biology chassis with the …
linked to health benefits. Furthermore, it is an emerging synthetic biology chassis with the …
Research and application of intelligent diagnosis and treatment engineering bacteria
N Zhao, J Chen, J Shi, Y Gao, L Li… - … in Bioengineering and …, 2024 - frontiersin.org
For over a century, scientists have been harnessing the therapeutic potential of bacteria in
treating diseases. The advent of synthetic biology in recent years has propelled the …
treating diseases. The advent of synthetic biology in recent years has propelled the …