Promising Drug Targets and Compounds with Anti-Toxoplasma gondii Activity

M Silva, C Teixeira, P Gomes, M Borges - Microorganisms, 2021 - mdpi.com
Toxoplasmosis is a parasitic disease caused by the globally distributed protozoan parasite
Toxoplasma gondii, which infects around one-third of the world population. This disease …

Toxoplasma gondii, Suicidal Behavior, and Intermediate Phenotypes for Suicidal Behavior

TT Postolache, A Wadhawan, D Rujescu… - Frontiers in …, 2021 - frontiersin.org
Within the general literature on infections and suicidal behavior, studies on Toxoplasma
gondii (T. gondii) occupy a central position. This is related to the parasite's neurotropism …

Global seroprevalence of Toxoplasma gondii infection among patients with mental and neurological disorders: A systematic review and meta‐analysis

H Bisetegn, H Debash, H Ebrahim… - Health Science …, 2023 - Wiley Online Library
Abstract Background and Aim Toxoplasmosis is the most widespread zoonotic disease that
affects one‐third of the world's population, and imposes a major public health problem …

Association between Toxoplasma gondii infection and psychiatric disorders: a cross-sectional study in China

T Liu, P Gao, D Bu, D Liu - Scientific Reports, 2022 - nature.com
Psychiatric patients have become the focus of public attention, and current research
suggests a possible link between Toxoplasma gondii (T. gondii) infection and mental illness …

Neurological and Neurobehavioral Disorders Associated with Toxoplasma gondii Infection in Humans

MA Virus, EG Ehrhorn, LAM Lui… - Journal of parasitology …, 2021 - Wiley Online Library
The intracellular parasite Toxoplasma gondii is estimated to infect up to 30% of the world
population, leading to lifelong chronic infection of the brain and muscle tissue. Although …

Arctigenin ameliorates depression-like behaviors in Toxoplasma gondii-infected intermediate hosts via the TLR4/NF-κB and TNFR1/NF-κB signaling pathways

JH Cheng, X Xu, YB Li, XD Zhao, F Aosai… - International …, 2020 - Elsevier
Toxoplasma gondii (T. gondii) is a known neurotropic protozoan that remains in the central
nervous system and induces neuropsychiatric diseases in intermediate hosts. Arctigenin …

Comparing the effectiveness of acceptance and commitment therapy and well-being therapy on life expectancy and psychological health in elderly nonclinical …

S Golestanifar, Z DashtBozorgi - Journal of Rafsanjan University …, 2021 - journal.rums.ac.ir
Materials and Methods: This study was a semi-experimental study with pretest and posttest
design with control group. The research population was elderly nonclinical depressed …

[HTML][HTML] Effectiveness of cognitive rehabilitation therapy on psychological distress and self-compassion in mastectomized Women with depression

MH Pourfereydoun, Z Dasht Bozorgi - Women's Health Bulletin, 2023 - journals.sums.ac.ir
Background: Mastectomy damages self-concept and sexual identity and also increases the
risk of depression due to changes in the physical appearance of patients. The present study …

Relationship between Toxoplasma gondii seropositivity and schizophrenia in the Lebanese population: potential implication of genetic polymorphism of MMP-9

A El Mouhawess, A Hammoud, M Zoghbi, S Hallit… - BMC psychiatry, 2020 - Springer
Background Toxoplasma multiplication and its persistence into the brain cause a local
neuroinflammatory reaction, resulting synthesis of neurotransmitters involved in neurological …

From the immune system to mood disorders especially induced by Toxoplasma gondii: CD4+ T cell as a bridge

Q Wang, Y Zhong, N Chen, J Chen - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Toxoplasma gondii (T. gondii), a ubiquitous and obligatory intracellular protozoa, not only
alters peripheral immune status, but crosses the blood-brain barrier to trigger brain …