A review on the mechanistic details of OXA enzymes of ESKAPE pathogens

FG Avci, I Tastekil, A Jaisi, P Ozbek Sarica… - … and Global Health, 2023 - Taylor & Francis
The production of β-lactamases is a prevalent mechanism that poses serious pressure on
the control of bacterial resistance. Furthermore, the unavoidable and alarming increase in …

Unlocking bacterial defense: exploring the potent inhibition of NorA efflux pump by coumarin derivatives in Staphylococcus aureus

ALAR Martin, RLS Pereira, JE Rocha, PAM Farias… - Microbial …, 2024 - Elsevier
The occurrence of bacterial resistance has been increasing, compromising the treatment of
various infections. The high virulence of Staphylococcus aureus allows for the maintenance …

[HTML][HTML] A Novel Tri-Hydroxy-Methylated Chalcone Isolated from Chromolaena tacotana with Anti-Cancer Potential Targeting Pro-Survival Proteins

G Mendez-Callejas, M Piñeros-Avila… - International Journal of …, 2023 - mdpi.com
Chromolaena tacotana (Klatt) RM King and H. Rob (Ch. tacotana) contains bioactive
flavonoids that may have antioxidant and/or anti-cancer properties. This study investigated …

[HTML][HTML] In silico study of inhibition effects of phytocompounds from four medicinal plants against the Staphylococcus aureus β-lactamase

F Etminani, A Etminani, SO Hasson, HK Judi… - Informatics in Medicine …, 2023 - Elsevier
Introduction This study aimed to evaluate new Staphylococcus aureus β-lactamase
inhibitors from medicinal plants Rosmarinus officinalis, Ocimum basilicum, Eucalyptus …

In silico study of essential oil of Bambusa vulgaris leaves as an anti beta-lactamase compound

PW Anggini, SA Amanina, SR Asyura… - Molecular and Cellular …, 2022 - cellbiopharm.com
Background: Klebsiella pneumoniae is known as an extended spectrum beta (β)-lactamases
(ESBLs)-producing bacteria, which produces enzymes that cause resistance to β-lactam …

Enhanced binding interaction and antibacterial inhibition for nanometal oxide particles activated with Aloe Vulgarize through one-pot ultrasonication techniques

NSF Dzulkharnien, R Rohani, NT Kofli, NAM Kasim… - Bioorganic …, 2024 - Elsevier
The interaction of green zinc oxide nanoparticles (ZnO NPs) with bacterial strains are still
scarcely reported. This work was conducted to study the green-one-pot-synthesized ZnO …

[HTML][HTML] Prediction of Phytochemicals for Their Potential to Inhibit New Delhi Metallo β-Lactamase (NDM-1)

Z Bibi, I Asghar, NM Ashraf, I Zeb, U Rashid, A Hamid… - Pharmaceuticals, 2023 - mdpi.com
The effectiveness of all antibiotics in the β-lactam group to cure bacterial infections has been
impaired by the introduction of the New Delhi Metallo-β-lactamase (NDM-1) enzyme …

[HTML][HTML] Antifungal activity and biocompatibility assessment with molecular docking and dynamic simulations of new pyrazole derivatives

BT Abd-Elhalim, GG El-Bana, AF El-Sayed… - BMC …, 2025 - pmc.ncbi.nlm.nih.gov
Background Because of their many bioactivities, which include psychoanalytic, antifungal,
antihypertensive, anti-inflammatory, and antiviral properties, pyrazoles and their derivatives …

Docking Studies on Biomolecules from Marine Microalga Skeletonema costatum Against Hemolysin Protein of Bioluminescence Disease-Causing Vibrio harveyi

K Sivakumar, S Kannappan, B Vijayakumar - Current Microbiology, 2023 - Springer
Grow-out and hatchery units of shrimps are being impacted by disease-causing bacterial
pathogens and predominantly marine Vibrios. The use of chemicals for governing bacterial …

Progress of the “Molecular Informatics” Section in 2022

A Rescifina - International Journal of Molecular Sciences, 2023 - mdpi.com
This is the first Editorial of the “Molecular Informatics” Section (MIS) of the International
Journal of Molecular Sciences (IJMS), which was created towards the end of 2018 (the first …