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High density lipoproteins: metabolism, function, and therapeutic potential
High Density Lipoproteins (HDLs) have long been considered as “good cholesterol,”
beneficial to the whole body and, in particular, to cardio-vascular health. However, HDLs are …
beneficial to the whole body and, in particular, to cardio-vascular health. However, HDLs are …
Coagulatory defects in type-1 and type-2 diabetes
AIS Sobczak, AJ Stewart - International journal of molecular sciences, 2019 - mdpi.com
Diabetes (both type-1 and type-2) affects millions of individuals worldwide. A major cause of
death for individuals with diabetes is cardiovascular diseases, in part since both types of …
death for individuals with diabetes is cardiovascular diseases, in part since both types of …
[HTML][HTML] Lipidome as a predictive tool in progression to type 2 diabetes in Finnish men
T Suvitaival, I Bondia-Pons, L Yetukuri, P Pöhö… - Metabolism, 2018 - Elsevier
Background There is a need for early markers to track and predict the development of type 2
diabetes mellitus (T2DM) from the state of normal glucose tolerance through prediabetes. In …
diabetes mellitus (T2DM) from the state of normal glucose tolerance through prediabetes. In …
[HTML][HTML] HDL triglycerides: a new marker of metabolic and cardiovascular risk
While cholesterol content in high-density lipoproteins (HDLs) is a well-established inverse
marker of cardiovascular risk, the importance of HDL–triglyceride (HDL-TG) concentration is …
marker of cardiovascular risk, the importance of HDL–triglyceride (HDL-TG) concentration is …
High-density lipoprotein (HDL) triglyceride and oxidized HDL: new lipid biomarkers of lipoprotein-related atherosclerotic cardiovascular disease
F Ito, T Ito - Antioxidants, 2020 - mdpi.com
Lipid markers are well-established predictors of vascular disease. The most frequently
measured lipid markers are total cholesterol, high-density lipoprotein (HDL)-cholesterol …
measured lipid markers are total cholesterol, high-density lipoprotein (HDL)-cholesterol …
Metabolomics in diabetic complications
LA Filla, JL Edwards - Molecular BioSystems, 2016 - pubs.rsc.org
With a global prevalence of 9%, diabetes is the direct cause of millions of deaths each year
and is quickly becoming a health crisis. Major long-term complications of diabetes arise from …
and is quickly becoming a health crisis. Major long-term complications of diabetes arise from …
HDL functionality in reverse cholesterol transport—Challenges in translating data emerging from mouse models to human disease
M Lee-Rueckert, JC Escola-Gil, PT Kovanen - Biochimica et Biophysica …, 2016 - Elsevier
Whereas LDL-derived cholesterol accumulates in atherosclerotic lesions, HDL particles are
thought to facilitate removal of cholesterol from the lesions back to the liver thereby …
thought to facilitate removal of cholesterol from the lesions back to the liver thereby …
Metabolomics and lipidomics profiling reveals hypocholesterolemic and hypolipidemic effects of arabinoxylan on type 2 diabetic rats
Q Nie, M **ng, H Chen, J Hu, S Nie - Journal of agricultural and …, 2019 - ACS Publications
Type 2 diabetes (T2D) is a pandemic disease chiefly characterized by hyperglycemia. In this
study, the combination of serum lipidomic and metabolomic approach was employed to …
study, the combination of serum lipidomic and metabolomic approach was employed to …
Relapsing-remitting multiple sclerosis patients display an altered lipoprotein profile with dysfunctional HDL
W Jorissen, E Wouters, JF Bogie, T Vanmierlo… - Scientific reports, 2017 - nature.com
Lipoproteins modulate innate and adaptive immune responses. In the chronic inflammatory
disease multiple sclerosis (MS), reports on lipoprotein level alterations are inconsistent and …
disease multiple sclerosis (MS), reports on lipoprotein level alterations are inconsistent and …
Particle size and cholesterol content of circulating HDL correlate with cardiovascular death in chronic heart failure
Evidence regarding any association of HDL-particle (HDL-P) derangements and HDL-
cholesterol content with cardiovascular (CV) death in chronic heart failure (HF) is lacking. To …
cholesterol content with cardiovascular (CV) death in chronic heart failure (HF) is lacking. To …