Vascular and haemodynamic issues of brain ageing

L Beishon, RH Clough, M Kadicheeni… - … -European Journal of …, 2021 - Springer
The population is ageing worldwide, thus increasing the burden of common age-related
disorders to the individual, society and economy. Cerebrovascular diseases (stroke …

Reliability and validity of the mean flow index (Mx) for assessing cerebral autoregulation in humans: a systematic review of the methodology

MH Olsen, CG Riberholt, J Mehlsen… - Journal of Cerebral …, 2022 - journals.sagepub.com
Cerebral autoregulation is a complex mechanism that serves to keep cerebral blood flow
relatively constant within a wide range of cerebral perfusion pressures. The mean flow index …

Methodological comparison of active-and passive-driven oscillations in blood pressure; implications for the assessment of cerebral pressure-flow relationships

JD Smirl, K Hoffman, YC Tzeng… - Journal of Applied …, 2015 - journals.physiology.org
We examined the between-day reproducibility of active (squat-stand maneuvers)-and
passive [oscillatory lower-body negative pressure (OLBNP) maneuvers]-driven oscillations …

Cerebral autoregulation, beta amyloid, and white matter hyperintensities are interrelated

AM Brickman, VA Guzman, M Gonzalez-Castellon… - Neuroscience …, 2015 - Elsevier
Emerging studies link vascular risk factors and cerebrovascular health to the prevalence and
rates of progression in Alzheimer's disease (AD). The brain's ability to maintain constant …

Dynamic cerebral autoregulation is transiently impaired for one week after large-vessel acute ischemic stroke

NH Petersen, S Ortega-Gutierrez, A Reccius… - Cerebrovascular …, 2015 - karger.com
Background: Dynamic cerebral autoregulation (DCA) is the continuous counterregulation of
cerebral blood flow to fluctuations in blood pressure. DCA can become impaired after acute …

Directional sensitivity of dynamic cerebral autoregulation in squat-stand maneuvers

RB Panerai, SC Barnes, M Nath… - American Journal …, 2018 - journals.physiology.org
Dynamic cerebral autoregulation (CA), the transient response of cerebral blood flow (CBF)
to rapid changes in arterial blood pressure (BP), is usually modeled as a linear mechanism …

[LIBRO][B] Cerebral blood flow and metabolism: a quantitative approach

SJ Payne - 2018 - World Scientific
The human brain is possibly the most complex organ in existence. This complexity means
that it is capable of great feats, yet has ensured that it remains surprisingly poorly …

Cerebral critical closing pressure and resistance-area product: the influence of dynamic cerebral autoregulation, age and sex

RB Panerai, VJ Haunton, O Llwyd… - Journal of Cerebral …, 2021 - journals.sagepub.com
Instantaneous arterial pressure-flow (or velocity) relationships indicate the existence of a
cerebral critical closing pressure (CrCP), with the slope of the relationship expressed by the …

The INfoMATAS project: methods for assessing cerebral autoregulation in stroke

DM Simpson, SJ Payne… - Journal of Cerebral Blood …, 2022 - journals.sagepub.com
Cerebral autoregulation refers to the physiological mechanism that aims to maintain blood
flow to the brain approximately constant when blood pressure changes. Impairment of this …

Hypertension and stroke in patients with left ventricular assist devices (LVADs)

JZ Willey, AK Boehme, F Castagna… - Current hypertension …, 2016 - Springer
Stroke is one of the most dreaded complications of left ventricular assist device therapy in
patients with end-stage congestive heart failure. There is strong evidence linking …