In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Raman microspectroscopy offers microbiologists a rapid and non-destructive technique to
assess the chemical composition of individual live microorganisms in near real time. In this …

All molecules consist of chemical bonds, and much can be learned from map** the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …

Tumorigenesis is dependent on the reprogramming of cellular metabolism as both direct
and indirect consequence of oncogenic mutations. A common feature of cancer cell …

Many human diseases, including metabolic, immune and central nervous system disorders,
as well as cancer, are the consequence of an alteration in lipid metabolic enzymes and their …

BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …

Stimulated Raman scattering (SRS) microscopy has shown enormous potential in revealing
molecular structures, dynamics, and couplings in complex systems. However, the sensitivity …

Increased glycolysis is considered as a hallmark of cancer. Yet, cancer cell metabolic
reprograming during therapeutic resistance development is under-studied. Here, through …

Cancer proliferation and progression involves altered metabolic pathways as a result of
continuous demand for energy and nutrients. In the last years, cell cycle regulators have …

Stimulated Raman scattering (SRS) describes a family of techniques first discovered and
developed in the 1960s. Whereas the nascent history of the technique is parallel to that of …