Glucose transporters at the blood-brain barrier: function, regulation and gateways for drug delivery
SG Patching - Molecular neurobiology, 2017 - Springer
Glucose transporters (GLUTs) at the blood-brain barrier maintain the continuous high
glucose and energy demands of the brain. They also act as therapeutic targets and provide …
glucose and energy demands of the brain. They also act as therapeutic targets and provide …
Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis
CP Chih, EL Roberts Jr - Journal of Cerebral Blood Flow & …, 2003 - journals.sagepub.com
Glucose had long been thought to fuel oxidative metabolism in active neurons until the
recently proposed astrocyte-neuron lactate shuttle hypothesis (ANLSH) challenged this …
recently proposed astrocyte-neuron lactate shuttle hypothesis (ANLSH) challenged this …
Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery
P Reinstrup, N Ståhl, P Mellergård, T Uski… - …, 2000 - journals.lww.com
OBJECTIVE The study was undertaken to measure baseline values for chemical markers in
human subjects during wakefulness, anesthesia, and neurosurgery, using intracerebral …
human subjects during wakefulness, anesthesia, and neurosurgery, using intracerebral …
Glucose transporters: structure, function and consequences of deficiency
GK Brown - Journal of inherited metabolic disease, 2000 - Springer
There are two mechanisms for glucose transport across cell membranes. In the intestine and
renal proximal tubule, glucose is transported against a concentration gradient by a …
renal proximal tubule, glucose is transported against a concentration gradient by a …
Fluctuations in brain glucose concentration during behavioral testing: dissociations between brain areas and between brain and blood
Traditional beliefs about two aspects of glucose regulation in the brain have been
challenged by recent findings. First, the absolute level of glucose in the brain's extracellular …
challenged by recent findings. First, the absolute level of glucose in the brain's extracellular …
Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease
M Bigl, MK Brückner, T Arendt, V Bigl… - Journal of neural …, 1999 - Springer
The activities of hexokinase, aldolase, pyruvate kinase, lactate dehydrogenase and glucose
6-phosphate dehydrogenase were determined in brains of patients with Alzheimer's disease …
6-phosphate dehydrogenase were determined in brains of patients with Alzheimer's disease …
Extracellular Glucose Concentrations in the Rat Hippocampus Measured byZero‐Net‐Flux: Effects of Microdialysis Flow Rate, Strain, andAge
The concentration of glucose in the brain's extracellularfluid remains controversial, with
recent estimates and measurements rangingfrom 0.35 to 3.3 mM. In the present …
recent estimates and measurements rangingfrom 0.35 to 3.3 mM. In the present …
Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain—an immunohistochemical study
M Arluison, M Quignon, P Nguyen, B Thorens… - Journal of chemical …, 2004 - Elsevier
The aim of this work was to study the distribution and cellular localization of GLUT2 in the rat
brain by light and electron microscopic immunohistochemistry, whereas our ultrastructural …
brain by light and electron microscopic immunohistochemistry, whereas our ultrastructural …
Lactate as a biomarker for sleep
E Naylor, DV Aillon, BS Barrett, GS Wilson… - Sleep, 2012 - academic.oup.com
Abstract Study Objectives: An ideal biomarker for sleep should change rapidly with sleep
onset, remain at a detectably differential level throughout the sleep period, and exhibit a …
onset, remain at a detectably differential level throughout the sleep period, and exhibit a …
Coordination of multiple memory systems
PE Gold - Neurobiology of learning and memory, 2004 - Elsevier
On the basis of lesions of different brain areas, several neural systems appear to be
important for processing information regarding different types of learning and memory. This …
important for processing information regarding different types of learning and memory. This …