[HTML][HTML] Role of zinc in immune system and anti-cancer defense mechanisms

D Skrajnowska, B Bobrowska-Korczak - Nutrients, 2019 - mdpi.com
The human body cannot store zinc reserves, so a deficiency can arise relatively quickly, eg,
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …

[HTML][HTML] The role of Fe, Zn, and Cu in pregnancy

K Grzeszczak, S Kwiatkowski, D Kosik-Bogacka - Biomolecules, 2020 - mdpi.com
Iron (Fe), copper (Cu), and zinc (Zn) are microelements essential for the proper functioning
of living organisms. These elements participatein many processes, including cellular …

Current understanding of ZIP and ZnT zinc transporters in human health and diseases

T Kambe, A Hashimoto, S Fujimoto - Cellular and molecular life sciences, 2014 - Springer
Abstract Zinc transporters, the Zrt-, Irt-like protein (ZIP) family and the Zn transporter (ZnT)
family transporters, are found in all aspects of life. Increasing evidence has clarified the …

Fetal programming of neuropsychiatric disorders

G Faa, M Manchia, R Pintus, C Gerosa… - … Research Part C …, 2016 - Wiley Online Library
Starting from the Developmental Origins of Health and Disease (DOHaD) hypotheses
proposed by David Barker, namely fetal programming, in the past years, there is a growing …

Trace elements as an activator of antioxidant enzymes.

M Wołonciej, E Milewska… - Postepy higieny i …, 2016 - europepmc.org
Oxidative stress is a state of impaired balance between the formation of free radicals and
antioxidant capacity of the body. It causes many defects of the body, eg lipid peroxidation …

Zinc and skin biology

Y Ogawa, T Kawamura, S Shimada - Archives of biochemistry and …, 2016 - Elsevier
Of all tissues, the skin has the third highest abundance of zinc in the body. In the skin, the
zinc concentration is higher in the epidermis than in the dermis, owing to a zinc requirement …

[HTML][HTML] Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers

A De Grande, S Leleu, E Delezie, C Rapp, S De Smet… - Poultry science, 2020 - Elsevier
Zinc is an essential nutritional trace element for all forms of life as it plays an important role
in numerous biological processes. In poultry, zinc is provided by in-feed supplementation …

Liver pathology in Wilson's disease: From copper overload to cirrhosis

C Gerosa, D Fanni, T Congiu, M Piras, F Cau… - Journal of inorganic …, 2019 - Elsevier
Wilson's disease (WD) is a genetic metabolic disease strictly associated with liver cirrhosis.
In this review, the genetic bases of the disease are discussed, with emphasis on the role of …

Metal ion interference therapy: metal-based nanomaterial-mediated mechanisms and strategies to boost intracellular “ion overload” for cancer treatment

Y Li, Y Wang, L Zhao, MH Stenzel, Y Jiang - Materials Horizons, 2024 - pubs.rsc.org
Metal ion interference therapy (MIIT) has emerged as a promising approach in the field of
nanomedicine for combatting cancer. With advancements in nanotechnology and tumor …

“Block and attack” strategy for tumor therapy through ZnO2/siRNA/NIR‐mediating Zn2+‐overload and amplified oxidative stress

Y Jiang, K Shao, F Zhang, T Wang, L Han, X Kong… - …, 2023 - Wiley Online Library
Abstract Intracellular zinc ion (Zn2+) accumulation disrupts the Zn2+ homeostasis, providing
an ion‐overloading anticancer strategy with great potential. The self‐adaptation of tumor …