[HTML][HTML] The barrier and interface mechanisms of the brain barrier, and brain drug delivery

S Zhang, L Gan, F Cao, H Wang, P Gong, C Ma… - Brain Research …, 2022 - Elsevier
Three different barriers are formed between the cerebrovascular and the brain parenchyma:
the blood-brain barrier (BBB), the blood-cerebrospinal fluid barrier (BCSFB), and the …

Quasistatic approximation in neuromodulation

B Wang, AV Peterchev, G Gaugain… - Journal of neural …, 2024 - iopscience.iop.org
We define and explain the quasistatic approximation (QSA) as applied to field modeling for
electrical and magnetic stimulation. Neuromodulation analysis pipelines include discrete …

High-definition cathodal direct current stimulation for treatment of acute ischemic stroke: a randomized clinical trial

M Bahr-Hosseini, K Nael, G Unal, M Iacoboni… - JAMA Network …, 2023 - jamanetwork.com
Importance Cathodal transcranial direct current stimulation (C-tDCS) provides
neuroprotection in preclinical models of acute ischemic stroke (AIS) by inhibiting peri-infarct …

[HTML][HTML] Neurovascular-modulation: a review of primary vascular responses to transcranial electrical stimulation as a mechanism of action

M Bahr-Hosseini, M Bikson - Brain Stimulation, 2021 - Elsevier
Background The ubiquitous vascular response to transcranial electrical stimulation (tES) has
been attributed to the secondary effect of neuronal activity forming the classic neurovascular …

Multi-scale multi-physics model of brain interstitial water flux by transcranial Direct Current Stimulation

N Khadka, C Poon, LM Cancel… - Journal of neural …, 2023 - iopscience.iop.org
Objective. Transcranial direct current stimulation (tDCS) generates sustained electric fields
in the brain, that may be amplified when crossing capillary walls (across blood-brain barrier …

Microglia contact cerebral vasculature through gaps between astrocyte endfeet

GP Morris, CG Foster… - Journal of Cerebral …, 2024 - journals.sagepub.com
The close spatial relationship between microglia and cerebral blood vessels implicates
microglia in vascular development, homeostasis and disease. In this study we used the …

Perspective: Disentangling the effects of tES on neurovascular unit

Y Arora, A Dutta - Frontiers in Neurology, 2023 - frontiersin.org
Transcranial electrical stimulation (tES) can modulate the neurovascular unit, including the
perivascular space morphology, but the mechanisms are unclear. In this perspective article …

[HTML][HTML] Efficacy and safety of HD-tDCS and respiratory rehabilitation for critically ill patients with COVID-19 The HD-RECOVERY randomized clinical trial

SM Andrade, MC de Araújo Silvestre, EÉT de França… - Brain Stimulation, 2022 - Elsevier
Abstract Background and purpose Acute Respiratory Distress Syndrome (ADRS) due to
coronavirus disease 2019 (COVID-19) has been associated with muscle fatigue …

Grey-box modeling and hypothesis testing of functional near-infrared spectroscopy-based cerebrovascular reactivity to anodal high-definition tDCS in healthy humans

Y Arora, P Walia, M Hayashibe… - PLoS computational …, 2021 - journals.plos.org
Transcranial direct current stimulation (tDCS) has been shown to evoke hemodynamics
response; however, the mechanisms have not been investigated systematically using …

Direct current stimulation modulates gene expression in isolated astrocytes with implications for glia-mediated plasticity

LM Cancel, D Silas, M Bikson, JM Tarbell - Scientific Reports, 2022 - nature.com
While the applications of transcranial direct current stimulation (tDCS) across brain disease
and cognition are diverse, they rely on changes in brain function outlasting stimulation. The …