The challenge and prospect of mRNA therapeutics landscape
Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …
in the pharmaceutical industry because they can be used for precise and individualized …
Dendritic cell-based immunotherapy
RL Sabado, S Balan, N Bhardwaj - Cell research, 2017 - nature.com
Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for
harnessing the potential of a patient's own immune system to eliminate tumor cells in …
harnessing the potential of a patient's own immune system to eliminate tumor cells in …
Dendritic cell–based cancer vaccines
PM Santos, LH Butterfield - The Journal of Immunology, 2018 - journals.aai.org
Dendritic cells (DC) are specialized immune cells that play a critical role in promoting an
immune response against Ags, which can include foreign pathogenic Ags and self-tumor …
immune response against Ags, which can include foreign pathogenic Ags and self-tumor …
Cancer immunotherapy via dendritic cells
K Palucka, J Banchereau - Nature Reviews Cancer, 2012 - nature.com
Cancer immunotherapy attempts to harness the power and specificity of the immune system
to treat tumours. The molecular identification of human cancer-specific antigens has allowed …
to treat tumours. The molecular identification of human cancer-specific antigens has allowed …
Vaccine delivery systems toward lymph nodes
Strategies of improving vaccine targeting ability toward lymph nodes have been attracting
considerable interest in recent years, though there are remaining delivery barriers based on …
considerable interest in recent years, though there are remaining delivery barriers based on …
Dendritic cell–based immunotherapy: state of the art and beyond
KF Bol, G Schreibelt, WR Gerritsen, IJM De Vries… - Clinical cancer …, 2016 - AACR
Dendritic cell (DC) vaccination in cancer patients aims to induce or augment an effective
antitumor immune response against tumor antigens and was first explored in a clinical trial …
antitumor immune response against tumor antigens and was first explored in a clinical trial …
Therapeutic cancer vaccines: past, present, and future
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …
to treat late stage disease by using a patient's own immune system. The promising results …
Dendritic cell vaccination of glioblastoma: road to success or dead end
A Datsi, RV Sorg - Frontiers in Immunology, 2021 - frontiersin.org
Glioblastomas (GBM) are the most frequent and aggressive malignant primary brain tumor
and remains a therapeutic challenge: even after multimodal therapy, median survival of …
and remains a therapeutic challenge: even after multimodal therapy, median survival of …
The clinical application of cancer immunotherapy based on naturally circulating dendritic cells
Dendritic cells (DCs) can initiate and direct adaptive immune responses. This ability is
exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor …
exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor …
[HTML][HTML] Pathways and therapeutic targets in melanoma
E Shtivelman, MA Davies, P Hwu, J Yang, M Lotem… - Oncotarget, 2014 - ncbi.nlm.nih.gov
This review aims to summarize the current knowledge of molecular pathways and their
clinical relevance in melanoma. Metastatic melanoma was a grim diagnosis, but in recent …
clinical relevance in melanoma. Metastatic melanoma was a grim diagnosis, but in recent …