Semen proteomics and male infertility

M Jodar, A Soler-Ventura, R Oliva… - Journal of …, 2017 - Elsevier
Semen is a complex body fluid containing an admixture of spermatozoa suspended in
secretions from the testes and epididymis which are mixed at the time of ejaculation with …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

Varicocoele and oxidative stress: New perspectives from animal and human studies

M Razi, M Tavalaee, F Sarrafzadeh‐Rezaei… - …, 2021 - Wiley Online Library
Background Varicocoele (VCL), one of the main causes of male subfertility, negatively
affects testicular function. Due to limited access to human testicular tissue, animal model …

[HTML][HTML] MicroRNA and male infertility: a potential for diagnosis

Y Khazaie, MHN Esfahani - International journal of fertility & sterility, 2014 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding single stranded RNA molecules that are
physiologically produced in eukaryotic cells to regulate or mostly down-regulate genes by …

The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition

B Nixon, EG Bromfield, MD Dun… - Asian Journal of …, 2015 - journals.lww.com
One of the most common lesions present in the spermatozoa of human infertility patients is
an idiopathic failure of sperm-egg recognition. Although this unique cellular interaction can …

Expression of sperm PLCζ and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion

M Tavalaee, M Nomikos, FA Lai… - Reproductive …, 2018 - Elsevier
Globozoospermia is characterized by the presence of 100% acrosomeless round-headed
spermatozoa in an ejaculate. Failed fertilization after intracytoplasmic sperm injection (ICSI) …

Heat shock protein A2 (HSPA2): regulatory roles in germ cell development and sperm function

B Nixon, EG Bromfield, J Cui, GN De Iuliis - … Role of Heat Shock Proteins in …, 2017 - Springer
Among the numerous families of heat shock protein (HSP) that have been implicated in the
regulation of reproductive system development and function, those belonging to the 70 kDa …

[HTML][HTML] Toward the identification of a subset of unexplained infertility: a sperm proteomic approach

S McReynolds, M Dzieciatkowska, J Stevens… - Fertility and …, 2014 - Elsevier
Objective To investigate the male gamete proteome and its relation to blastocyst
development and reproductive success. Design Experimental study. Setting Research …

[HTML][HTML] Heat stress and stallion fertility

M Shakeel, M Yoon - Journal of animal science and technology, 2023 - ncbi.nlm.nih.gov
The threat posed by increased surface temperatures worldwide has attracted the attention of
researchers to the reaction of animals to heat stress. Spermatogenesis in animals such as …

Improving sperm oxidative stress and embryo quality in advanced paternal age using idebenone in vitro—A proof-of-concept study

V Nikitaras, D Zander-Fox, NO McPherson - Antioxidants, 2021 - mdpi.com
Advanced paternal age is associated with increased sperm reactive oxygen species (ROS)
and decreased fertilization and pregnancy rates. Sperm washing during infertility treatment …