Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

Nanomedicines refers to nanotechnology inspired pharmaceutical products often referred to
as 'nanopharmaceuticals.'It has displayed commendable potential in enhancing therapeutic …

Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …

Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …

Highlights•CNT-based target-specific drug delivery is a promising approach to circumvent
the limitations of nonspecific therapeutic agents.•Interactions between the drug, CNT and …

Dendrimers are multifunctional carriers widely employed for delivering drugs in a variety of
disease conditions including HIV/AIDS and cancer. Albendazole (ABZ) is a commonly used …

Highlights•Nanotechnology can protect siRNA against RNAse degradation.•siRNA adopts
an alternative pathway to knock genes with high specificity to cure cancer.•An ideal vector is …

Chemoresistance is the refractoriness of the cancer cells to the commonly used
chemotherapeutic agents. It is one of the significant challenges in the treatment of cancer. To …

Most of the biologically active compounds are struggle with low solubility and therefore low
bioavailability, biological degradation and inadvertent intrinsic side effects. To overcome …