Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …

Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Virus entry, consisting of attachment to and penetration into the host target cell, is the first
step of the virus life cycle and is a critical 'do or die'event that governs virus emergence in …

Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …

Detection of viruses by innate immune sensors induces protective antiviral immunity. The
viral DNA sensor cyclic GMP-AMP synthase (cGAS) is necessary for detection of HIV by …

MHC-I-associated peptides deriving from non-coding genomic regions and mutations can
generate tumor-specific antigens, including neoantigens. Quantifying tumor-specific …

Splenic CD169+ macrophages are located in the marginal zone to efficiently capture blood-
borne pathogens. Here, we investigate the requirements for the induction of CD8+ T cell …

Inefficient and abnormal clearance of apoptotic cells (efferocytosis) contributes to systemic
autoimmune disease in humans and mice, and inefficient chromosomal DNA degradation by …