Molecular basis of pathogenesis of FMDV
PW Mason, MJ Grubman, B Baxt - Virus research, 2003 - Elsevier
Current understanding of the molecular basis of pathogenesis of foot-and-mouth disease
(FMD) has been achieved through over 100 years of study into the biology of the etiologic …
(FMD) has been achieved through over 100 years of study into the biology of the etiologic …
Mutational and fitness landscapes of an RNA virus revealed through population sequencing
A Acevedo, L Brodsky, R Andino - Nature, 2014 - nature.com
RNA viruses exist as genetically diverse populations. It is thought that diversity and genetic
structure of viral populations determine the rapid adaptation observed in RNA viruses and …
structure of viral populations determine the rapid adaptation observed in RNA viruses and …
Picornaviruses: a view from 3A
T Jackson, GJ Belsham - Viruses, 2021 - mdpi.com
Picornaviruses are comprised of a positive-sense RNA genome surrounded by a protein
shell (or capsid). They are ubiquitous in vertebrates and cause a wide range of important …
shell (or capsid). They are ubiquitous in vertebrates and cause a wide range of important …
RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region
T Yamashita, S Kaneko, Y Shirota, W Qin… - Journal of Biological …, 1998 - ASBMB
The hepatitis C virus (HCV) NS5B protein encodes an RNA-dependent RNA polymerase
(RdRP), which is the central catalytic enzyme of HCV replicase. We established a new …
(RdRP), which is the central catalytic enzyme of HCV replicase. We established a new …
Determinants of membrane association for poliovirus protein 3AB
Poliovirus protein 3AB may serve as the lipophilic carrier of a protein primer (VPg or 3B)
used for the initiation of genomic viral RNA synthesis. In order to study the membrane …
used for the initiation of genomic viral RNA synthesis. In order to study the membrane …
Kissing of the two predominant hairpin loops in the coxsackie B virus 3'untranslated region is the essential structural feature of the origin of replication required for …
Higher-order RNA structures in the 3'untranslated region (3'UTR) of enteroviruses are
thought to play a pivotal role in viral negative-strand RNA synthesis. The structure of the …
thought to play a pivotal role in viral negative-strand RNA synthesis. The structure of the …
Design and molecular docking studies of {N1-[2-(amino)ethyl]ethane-1,2-diamine}-[tris(oxido)]-molybdenum(VI) complex as a potential antivirus drug: from synthesis …
The aim of this study was to synthesize and examine the molecular docking of a Mo (VI)
complex [Mo (dien) O3](1),{N1-[2-(amino) ethyl] ethane-1, 2-diamine}-[tris (oxido)] …
complex [Mo (dien) O3](1),{N1-[2-(amino) ethyl] ethane-1, 2-diamine}-[tris (oxido)] …
Potyvirus Genome-Linked Protein (VPg) Determines Pea Seed-Borne Mosaic Virus Pathotype-Specific Virulence in Pisum sativum
The mechanism of Pisum sativum pathotype-specific resistance to pea seed-borne mosaic
potyvirus (PSbMV) was investigated and the coding region determinant of PSbMV virulence …
potyvirus (PSbMV) was investigated and the coding region determinant of PSbMV virulence …
Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus
AV Paul, J Peters, JA Mugavero, J Yin… - Journal of …, 2003 - Am Soc Microbiol
The first step in poliovirus (PV) RNA synthesis is the covalent linkage of UMP to the terminal
protein VPg. This reaction can be studied in vitro with two different assays. The simpler …
protein VPg. This reaction can be studied in vitro with two different assays. The simpler …
Subcellular distribution of the foot-and-mouth disease virus 3A protein in cells infected with viruses encoding wild-type and bovine-attenuated forms of 3A
VK O'Donnell, JM Pacheco, TM Henry, PW Mason - Virology, 2001 - Elsevier
Picornavirus infection induces the proliferation and rearrangement of intracellular
membranes in response to the synthesis of nonstructural proteins, including 3A. We have …
membranes in response to the synthesis of nonstructural proteins, including 3A. We have …