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[HTML][HTML] Current advances in Zika vaccine development
Y Wang, L Ling, Z Zhang, A Marin-Lopez - Vaccines, 2022 - mdpi.com
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …
Epizootic hemorrhagic disease virus: current knowledge and emerging perspectives
Epizootic Hemorrhagic Disease (EHD) of ruminants is a viral pathology that has significant
welfare, social, and economic implications. The causative agent, epizootic hemorrhagic …
welfare, social, and economic implications. The causative agent, epizootic hemorrhagic …
A mosquito salivary protein-driven influx of myeloid cells facilitates flavivirus transmission
Z Wang, K Nie, Y Liang, J Niu, X Yu, O Zhang… - The EMBO …, 2024 - embopress.org
Mosquitoes transmit many disease-relevant flaviviruses. Efficient viral transmission to
mammalian hosts requires mosquito salivary factors. However, the specific salivary …
mammalian hosts requires mosquito salivary factors. However, the specific salivary …
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
Transmission from an infected mosquito to a host is an essential process in the life cycle of
mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva …
mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva …
Malaria: influence of Anopheles mosquito saliva on Plasmodium infection
Malaria is caused by Plasmodium protozoa that are transmitted by anopheline mosquitoes.
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …
Understanding pathogen survival and transmission by arthropod vectors to prevent human disease
Many endemic poverty-associated diseases, such as malaria and leishmaniasis, are
transmitted by arthropod vectors. Pathogens must interact with specific molecules in the …
transmitted by arthropod vectors. Pathogens must interact with specific molecules in the …
An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms
Vector-borne diseases are a leading cause of death worldwide and pose a substantial
unmet medical need. Pathogens binding to host extracellular proteins (the" exoproteome") …
unmet medical need. Pathogens binding to host extracellular proteins (the" exoproteome") …
The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity
The Aedes aegypti mosquito is a vector of many infectious agents, including flaviviruses
such as Zika virus. Components of mosquito saliva have pleomorphic effects on the …
such as Zika virus. Components of mosquito saliva have pleomorphic effects on the …
Safety and immunogenicity of a mosquito saliva peptide-based vaccine: a randomised, placebo-controlled, double-blind, phase 1 trial
Background In animal models, immunity to mosquito salivary proteins protects animals
against mosquito-borne disease. These findings provide a rationale to vaccinate against …
against mosquito-borne disease. These findings provide a rationale to vaccinate against …
Aedes Mosquito Salivary Components and Their Effect on the Immune Response to Arboviruses
Vector-borne diseases are responsible for over a billion infections each year and nearly one
million deaths. Mosquito-borne dengue virus, West Nile, Japanese encephalitis, Zika …
million deaths. Mosquito-borne dengue virus, West Nile, Japanese encephalitis, Zika …