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[HTML][HTML] Superoxide dismutase administration: A review of proposed human uses
AC Rosa, D Corsi, N Cavi, N Bruni, F Dosio - Molecules, 2021 - mdpi.com
Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …
Cellular evaluation of superoxide dismutase mimics as catalytic drugs: Challenges and opportunities
Oxidative stress is known to be associated with many pathologies including inflammation,
cancer, diabetes, etc. However, oxidative stress resulting from the imbalance between …
cancer, diabetes, etc. However, oxidative stress resulting from the imbalance between …
ROS scavenging of SOD/CAT mimics probed by EPR and reduction of lipid peroxidation in S. cerevisiae and mouse liver, under severe hydroxyl radical stress …
LB Menezes, BB Segat, H Tolentino, DC Pires… - Journal of inorganic …, 2023 - Elsevier
The interaction between Cu II, Fe III and Mn II complexes, derived from the ligands 1-[bis
(pyridine-2-ylmethyl) amino]-3-chloropropan-2-ol (hpclnol) and bis (pyridine-2-ylmethyl) …
(pyridine-2-ylmethyl) amino]-3-chloropropan-2-ol (hpclnol) and bis (pyridine-2-ylmethyl) …
In vivo visualization of enantioselective targeting of amyloid and improvement of cognitive function by clickable chiral metallohelices
The pathogenesis of Alzheimer's disease (AD) is closely related to several contributing
factors, especially amyloid-β (Aβ) aggregation. Bioorthogonal reactions provide a general …
factors, especially amyloid-β (Aβ) aggregation. Bioorthogonal reactions provide a general …
The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae
Molecular causes of aging and longevity interventions have witnessed an upsurge in the last
decade. The resurgent interests in the application of small molecules as potential …
decade. The resurgent interests in the application of small molecules as potential …
[HTML][HTML] Antitumoral synergism between a copper (II) complex and cisplatin improves in vitro and in vivo anticancer activity against melanoma, lung and breast cancer …
D Mariani, Z Ghasemishahrestani, W Freitas… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Background Intrinsic resistance of cancer cells is a major concern for the success of
chemotherapy, and this undesirable feature stimulates further research into the design of …
chemotherapy, and this undesirable feature stimulates further research into the design of …
Mitigating methylglyoxal-induced glycation stress: the protective role of iron, copper, and manganese coordination compounds in Saccharomyces cerevisiae
MESF do Espírito Santo, BF Frascino… - Biochemical …, 2024 - portlandpress.com
Glycation-induced stress (G-iS) is a physiological phenomenon that leads to the formation of
advanced glycation end-products, triggering detrimental effects such as oxidative stress …
advanced glycation end-products, triggering detrimental effects such as oxidative stress …
Iron and copper complexes with antioxidant activity as inhibitors of the metastatic potential of glioma cells
Gliomas are the most common type of primary brain tumors, presenting high mortality and
recurrence rates that highlight the need for the development of more efficient therapies. In …
recurrence rates that highlight the need for the development of more efficient therapies. In …
Response and regulatory mechanisms of heat resistance in pathogenic fungi
W **ao, J Zhang, J Huang, C **n, MJ Li… - Applied Microbiology and …, 2022 - Springer
Both the increasing environmental temperature in nature and the defensive body
temperature response to pathogenic fungi during mammalian infection cause heat stress …
temperature response to pathogenic fungi during mammalian infection cause heat stress …
Scavenging of reactive species probed by EPR and ex-vivo nanomolar reduction of lipid peroxidation of manganese complexes
BB Segat, LB Menezes, R Cervo, R Cargnelutti… - Journal of Inorganic …, 2023 - Elsevier
Antioxidant activity toward H 2 O 2, anion radical superoxide, hydroxyl and DPPH (2, 2-
diphenyl-1-picrylhydrazyl) of two manganese complexes [Mn (III)(bpa) 2] Cl. H 2 O (1) and …
diphenyl-1-picrylhydrazyl) of two manganese complexes [Mn (III)(bpa) 2] Cl. H 2 O (1) and …