Polygenic scores in cancer

X Yang, S Kar, AC Antoniou, PDP Pharoah - Nature reviews Cancer, 2023 - nature.com
Since the publication of the first genome-wide association study for cancer in 2007,
thousands of common alleles that are associated with the risk of cancer have been …

Acceptability of risk stratification within population‐based cancer screening from the perspective of the general public: A mixed‐methods systematic review

LC Taylor, A Hutchinson, K Law, V Shah… - Health …, 2023 - Wiley Online Library
Introduction Risk‐stratified cancer screening has the potential to improve resource allocation
and the balance of harms and benefits by targeting those most likely to benefit. Public …

Acceptability of risk stratification within population-based cancer screening from the perspective of healthcare professionals: A mixed methods systematic review and …

LC Taylor, K Law, A Hutchinson, RA Dennison… - PLoS …, 2023 - journals.plos.org
Background Introduction of risk stratification within population-based cancer screening
programmes has the potential to optimise resource allocation by targeting screening …

Risk prediction models for oral cancer: A systematic review

A Espressivo, ZS Pan, JA Usher-Smith, H Harrison - Cancers, 2024 - mdpi.com
Simple Summary Oral cancer is among the twenty most common cancers worldwide.
Finding and treating this cancer early improves survival rates. Screening the whole …

Association between metabolic syndrome and kidney cancer risk: a prospective cohort study

L Wang, H Du, C Sheng, H Dai, K Chen - Lipids in Health and Disease, 2024 - Springer
Background Kidney cancer has become known as a metabolic disease. However, there is
limited evidence linking metabolic syndrome (MetS) with kidney cancer risk. This study …

[HTML][HTML] Risk-stratified screening for the early detection of kidney cancer

SH Rossi, H Harrison, JA Usher-Smith, GD Stewart - The Surgeon, 2024 - Elsevier
Earlier detection and screening for kidney cancer has been identified as a key research
priority, however the low prevalence of the disease in unselected populations limits the cost …

[HTML][HTML] Development of a Polygenic Risk Score for Metabolic Dysfunction-Associated Steatotic Liver Disease Prediction in UK Biobank

P Giardoglou, I Gavra, AI Amanatidou, IP Kalafati… - Genes, 2024 - mdpi.com
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the
leading cause of liver-related morbidity and mortality. Although the invasive liver biopsy …

[HTML][HTML] 2022 WUOF/SIU International Consultation on Urological Diseases: Kidney Cancer Screening and Epidemiology

SH Rossi, H Tanaka, JA Usher-Smith… - Société Internationale d …, 2022 - mdpi.com
The incidence of renal cell carcinoma (RCC) has risen worldwide over the past few
decades, and this has been associated with a stage shift. Survival outcomes of RCC depend …

Comprehensive prognostic assessment in kidney cancer: A multidimensional approach analyzing Fufang Sanling granules, genetic variants, and immune infiltration

J Zhu, Y Ye, X Zhao, M Wu, X Wang… - Environmental …, 2024 - Wiley Online Library
This study delves into the potential therapeutic benefits of Fufang Sanling Granules for
kidney cancer, focusing on their active components and the underlying mechanisms of their …

Risk Prediction Models for Oral Cancer: A Systematic Review. Cancers 2024, 16, 617

A Espressivo, ZS Pan, JA Usher-Smith, H Harrison - 2024 - europepmc.org
In the last 30 years, there has been an increasing incidence of oral cancer worldwide.
Earlier detection of oral cancer has been shown to improve survival rates. However, given …