[HTML][HTML] Recent trends on wound management: New therapeutic choices based on polymeric carriers

ME Okur, ID Karantas, Z Şenyiğit, NÜ Okur… - Asian Journal of …, 2020 - Elsevier
Wound healing is an unmet therapeutic challenge among medical society since wound
assessment and management is a complex procedure including several factors playing …

Therapeutic potential of nanocarrier-mediated delivery of phytoconstituents for wound healing: their current status and future perspective

M Kumar, P Keshwania, S Chopra, S Mahmood… - AAPS …, 2023 - Springer
The treatment of wounds is a serious problem all over the world and imposes a huge
financial burden on each and every nation. For a long time, researchers have explored …

[HTML][HTML] An alternative approach to wound healing field; new composite films from natural polymers for mupirocin dermal delivery

NÜ Okur, N Hökenek, ME Okur, Ş Ayla, A Yoltaş… - Saudi Pharmaceutical …, 2019 - Elsevier
In this study, novel adhesive films were prepared for Mupirocin dermal delivery. Natural
polymers as chitosan, sodium alginate and carbopol were used for films development to …

Improving therapeutic efficacy of voriconazole against fungal keratitis: Thermo-sensitive in situ gels as ophthalmic drug carriers

NÜ Okur, V Yozgatlı, ME Okur, A Yoltaş… - Journal of drug delivery …, 2019 - Elsevier
The aim of this research was to evaluate the potential use of in situ gel formulations for
voriconazole ocular delivery as fungal keratitis treatment. The in situ gelling system was …

Highly ordered functionalized mesoporous silicate nanoparticles reinforced poly (lactic acid) gatekeeper surface for infection treatment

MF Abdelbar, RS Shams, OM Morsy, MA Hady… - International journal of …, 2020 - Elsevier
The controlled release of a drug considers the key feature of the delivery carrier that
enhances therapeutic efficacy. This study was aimed at design, synthesis of nano valve and …

Novel linezolid loaded bio-composite films as dressings for effective wound healing: experimental design, development, optimization, and antimicrobial activity

DS Ghataty, RI Amer, R Wasfi, RN Shamma - Drug Delivery, 2022 - Taylor & Francis
Biphasic release bio-composite films of the low water-soluble drug, linezolid (LNZ), were
formulated using the solvent casting technique. Different polymers and plasticizers (gelatin …

In vitro–in vivo evaluation of tetrahydrozoline‐loaded ocular in situ gels on rabbits for allergic conjunctivitis management

NÜ Okur, V Yozgatli, ME Okur - Drug Development Research, 2020 - Wiley Online Library
Ocular allergy is one of the most common disorders of the eye surface. The conventional eye
drops lack of therapeutic efficacy due to low ocular bioavailability and decreased drug …

New therapeutic system based on hydrogels for vaginal candidiasis management: formulation–characterization and in vitro evaluation based on vaginal irritation and …

MD Arpa, A Yoltaş, E Onay Tarlan… - Pharmaceutical …, 2020 - Taylor & Francis
The objective of the present research was to examine the possible usage of terbinafine
loaded hydrogels for vaginal application as part of vaginal candidiasis treatment. Vaginal …

Chitosan-bovine serum albumin-Carbopol 940 nanogels for mupirocin dermal delivery: ex-vivo permeation and evaluation of cellular binding capacity via …

Z Ay Şenyiğit, N Coşkunmeriç, EŞ Çağlar… - Pharmaceutical …, 2021 - Taylor & Francis
The goal of this study was to develop and examine the nanogel-based topical delivery
system of mupirocin. Nanogels were prepared with chitosan and bovine serum albumin by …

Tazarotene-loaded in situ gels for potential management of psoriasis: biocompatibility, anti-inflammatory and analgesic effect

İ Erol, N Üstündağ Okur, D Orak, H Sipahi… - Pharmaceutical …, 2020 - Taylor & Francis
Psoriasis is a chronic autoinflammatory disorder characterized by patches of abnormal skin.
For psoriasis management, the application of topical retinoids as Tazarotene is …