International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia

GF Watts, SS Gidding, RA Hegele, FJ Raal… - Nature Reviews …, 2023 - nature.com
This contemporary, international, evidence-informed guidance aims to achieve the greatest
good for the greatest number of people with familial hypercholesterolaemia (FH) across …

Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism

J Ghouse, V Tragante, G Ahlberg, SA Rand… - Nature …, 2023 - nature.com
We report a genome-wide association study of venous thromboembolism (VTE)
incorporating 81,190 cases and 1,419,671 controls sampled from six cohorts. We identify 93 …

Yellow Himalayan Raspberry (Rubus ellipticus Sm.): Ethnomedicinal, Nutraceutical, and Pharmacological Aspects

A Lamichhane, G Lamichhane, HP Devkota - Molecules, 2023 - mdpi.com
Yellow Himalayan raspberry (Rubus ellipticus Sm., Rosaceae) is a native species of the
Indian subcontinent, Southern China, and the Philippines, which has been historically used …

[HTML][HTML] Revolutionizing cardiac care: a comprehensive narrative review of cardiac rehabilitation and the evolution of cardiovascular medicine

A Ullah, M Kumar, M Sayyar, FNU Sapna, C John… - Cureus, 2023 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) stands as a global health crisis, with its complex web of
conditions, including coronary artery disease, heart failure, hypertension, and stroke …

Clinical utility of polygenic scores for cardiometabolic disease in Arabs

I Shim, H Kuwahara, NN Chen, MO Hashem… - Nature …, 2023 - nature.com
Arabs account for 5% of the world population and have a high burden of cardiometabolic
disease, yet clinical utility of polygenic risk prediction in Arabs remains understudied. Among …

Subty** severe hypercholesterolemia by genetic determinant to stratify risk of coronary artery disease

ASF Berry, LK Jones, EJ Sijbrands… - … and Vascular Biology, 2023 - Am Heart Assoc
BACKGROUND: Severe hypercholesterolemia, defined as LDL (low-density lipoprotein)
cholesterol (LDL-C) measurement≥ 190 mg/dL, is associated with increased risk for …

Impact of healthy lifestyle in patients with familial hypercholesterolemia

H Tada, N Kojima, K Yamagami, A Nomura, A Nohara… - JACC: Asia, 2023 - jacc.org
Background Pathogenic mutations are associated with poor outcomes in patients with
familial hypercholesterolemia (FH). However, data on the effects of a healthy lifestyle on FH …

Construction and validation of a predictive model for coronary artery disease using extreme gradient boosting

Z Zhang, B Shao, H Liu, B Huang, X Gao… - Journal of …, 2024 - Taylor & Francis
Purpose Early recognition of coronary artery disease (CAD) could delay its progress and
significantly reduce mortality. Sensitive, specific, cost-efficient and non-invasive indicators …

Genomic Drivers of Coronary Artery Disease and Risk of Future Outcomes After Coronary Angiography

K Supriami, SM Urbut, JR Tello-Ayala, O Unlu… - JAMA Network …, 2025 - jamanetwork.com
Importance Disease characteristics of genetically mediated coronary artery disease (CAD)
on coronary angiography and the association of genomic risk with outcomes after coronary …

Clinical applications of polygenic risk score for coronary artery disease through the life course

AC Fahed, P Natarajan - Atherosclerosis, 2023 - Elsevier
Coronary artery disease (CAD) remains a leading cause of morbidity and mortality
worldwide, highlighting the limitations of current primary and secondary prevention …