Recent advances in the direct functionalization of quinoxalin-2 (1 H)-ones

Q Ke, G Yan, J Yu, X Wu - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
The direct C3-functionalization of quinoxalin-2 (1H)-ones via C–H bond activation has
recently attracted considerable attention, due to their diverse biological activities and …

Green strategies for transition metal-catalyzed C–H activation in molecular syntheses

U Dhawa, N Kaplaneris, L Ackermann - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
Transition metal catalyzed C–H activation has surfaced as a powerful tool to improve the
efficacy of molecular synthesis. Last two decades have witnessed a considerable progress …

Recent Progress toward the Introduction of Functionalized Difluoromethylated Building Blocks onto C(sp2) and C(sp) Centers

MC Belhomme, T Besset, T Poisson… - … A European Journal, 2015 - Wiley Online Library
Fluorine chemistry is a field undergoing tremendous expansion. Although much attention
has been paid to the introduction of the fluorine atom and the CF3 group, less interest has …

Radical perfluoroalkylation of aliphatic substrates

DE Yerien, S Barata-Vallejo, A Postigo - ACS Catalysis, 2023 - ACS Publications
A selection of perfluoroalkylation reactions of aliphatic substrates that display
methodological and synthetic amplitude will be studied, giving examples of their …

Palladium‐Catalyzed Directed para C−H Functionalization of Phenols

T Patra, S Bag, R Kancherla, A Mondal… - Angewandte Chemie …, 2016 - Wiley Online Library
Various practical methods for the selective C− H functionalization of the ortho and recently
also of the meta position of an arene have already been developed. Following our recent …

Heterogeneous catalytic approaches in C–H activation reactions

S Santoro, SI Kozhushkov, L Ackermann, L Vaccaro - Green Chemistry, 2016 - pubs.rsc.org
Despite the undisputed advances and progress in metal-catalyzed C–H functionalizations,
this atom-economical approach had thus far largely been developed with the aid of various …

Direct alkylation of heteroarenes with unactivated bromoalkanes using photoredox gold catalysis

T McCallum, L Barriault - Chemical Science, 2016 - pubs.rsc.org
Although visible light photoredox catalysis has emerged as a powerful tool for the
construction of C–C bonds, common catalysts and/or their photoexcited states suffer from …

Intermolecular hydropyridylation of unactivated alkenes

X Ma, SB Herzon - Journal of the American Chemical Society, 2016 - ACS Publications
A general method for the hydropyridylation of unactivated alkenes is described. The
transformation connects metal-mediated hydrogen atom transfer to alkenes and Minisci …

Hydroheteroarylation of Unactivated Alkenes Using N-Methoxyheteroarenium Salts

X Ma, H Dang, JA Rose, P Rablen… - Journal of the American …, 2017 - ACS Publications
We report the first reductive coupling of unactivated alkenes with N-methoxy pyridazinium,
imidazolium, quinolinium, and isoquinolinium salts under hydrogen atom transfer (HAT) …

Versatile cross-dehydrogenative coupling of heteroaromatics and hydrogen donors via decatungstate photocatalysis

MC Quattrini, S Fujii, K Yamada, T Fukuyama… - Chemical …, 2017 - pubs.rsc.org
A facile sunlight-induced derivatization of heteroaromatics via photocatalyzed C–H
functionalization in amides, ethers, alkanes and aldehydes is described …