Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

Resident memory T cells (TRM) form a distinct type of T memory cells that stably resides in
tissues. TRM form an integral part of the immune sensing network and have the ability to …

Tissue-resident memory T cells (TRM cells) provide protective immunity, but the
contributions of specific tissue environments to TRM cell differentiation and homeostasis are …

CD8+ T cell exhaustion dampens antitumor immunity. Although several transcription factors
have been identified that regulate T cell exhaustion, the molecular mechanisms by which …

Tissue localization is a critical determinant of T cell immunity. CD8+ T cells are contact-
dependent killers, which requires them to physically be within the tissue of interest to kill …

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is
activated by small molecules provided by the diet, microorganisms, metabolism, and …

CD69 is a membrane‐bound, type II C‐lectin receptor. It is a classical early marker of
lymphocyte activation due to its rapid appearance on the surface of the plasma membrane …

Vitiligo is an autoimmune depigment disease results from extensive melanocytes
destruction. The destruction of melanocyte is thought to be of multifactorial causation …

Memory B cells are found in lymphoid and non-lymphoid tissues, suggesting that some may
be tissue-resident cells. Here we show that pulmonary influenza infection elicited lung …

Tissue-resident memory T cells (TRM cells) provide rapid and superior control of localized
infections. While the transcription factor Runx3 is a critical regulator of CD8+ T cell tissue …