Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Alzheimer's disease (AD) is a complex, heterogeneous, progressive disease and is the most
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …

The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

BACKGROUND. Noninvasive detection of Alzheimer's disease (AD) with high specificity and
sensitivity can greatly facilitate identification of at-risk populations for earlier, more effective …

Topic OCT is a noninvasive tool to measure specific retinal layers in the eye. The
relationship of retinal spectral-domain (SD) OCT measurements with Alzheimer's disease …

Hypertensive eye disease includes a spectrum of pathological changes, the most well
known being hypertensive retinopathy. Other commonly involved parts of the eye in …

Purpose Evaluate and compare the retinal microvasculature in the superficial capillary
plexus (SCP) in Alzheimer's disease (AD), mild cognitive impairment (MCI), and cognitively …

Pericyte loss and deficient vascular platelet-derived growth factor receptor-β (PDGFRβ)
signaling are prominent features of the blood–brain barrier breakdown described in …

Although historically perceived as a disorder confined to the brain, our understanding of
Alzheimer's disease (AD) has expanded to include extra-cerebral manifestation, with …

Age-related macular degeneration (AMD) and glaucoma are degenerative conditions of the
retina and a significant cause of irreversible blindness in developed countries. Alzheimer's …