[HTML][HTML] Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear

TB Lonsdorf, MM Menz, M Andreatta… - Neuroscience & …, 2017 - Elsevier
The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Updated meta‐analysis of classical fear conditioning in the anxiety disorders

P Duits, DC Cath, S Lissek, JJ Hox… - Depression and …, 2015 - Wiley Online Library
The aim of the current study was twofold:(1) to systematically examine differences in fear
conditioning between anxiety patients and healthy controls using meta‐analytic methods …

Fear extinction in the human brain: A meta-analysis of fMRI studies in healthy participants

MA Fullana, A Albajes-Eizagirre, C Soriano-Mas… - Neuroscience & …, 2018 - Elsevier
The study of fear extinction represents an important example of translational neuroscience in
psychiatry and promises to improve the understanding and treatment of anxiety and fear …

More than just noise: Inter-individual differences in fear acquisition, extinction and return of fear in humans-Biological, experiential, temperamental factors, and …

TB Lonsdorf, CJ Merz - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Why do only some individuals develop pathological anxiety following adverse events? Fear
acquisition, extinction and return of fear paradigms serve as experimental learning models …

[HTML][HTML] Neuroinflammation-associated alterations of the brain as potential neural biomarkers in anxiety disorders

E Won, YK Kim - International Journal of Molecular Sciences, 2020 - mdpi.com
Stress-induced changes in the immune system, which lead to neuroinflammation and
consequent brain alterations, have been suggested as possible neurobiological substrates …

Neuroimaging of fear-associated learning

JA Greco, I Liberzon - Neuropsychopharmacology, 2016 - nature.com
Fear conditioning has been commonly used as a model of emotional learning in animals
and, with the introduction of functional neuroimaging techniques, has proven useful in …

How can neurobiology of fear extinction inform treatment?

MG Craske, CF Sandman, MB Stein - Neuroscience & Biobehavioral …, 2022 - Elsevier
The neurobiology of extinction learning has been translated to inform the delivery of
exposure therapy, the gold-standard treatment for fear and anxiety disorders. The inhibitory …

Common and distinct neural correlates of fear extinction and cognitive reappraisal: a meta-analysis of fMRI studies

M Picó-Pérez, M Alemany-Navarro… - Neuroscience & …, 2019 - Elsevier
Cognitive reappraisal and fear extinction learning represent two different approaches to
emotion regulation. While their respective neural correlates have been widely studied with …

Predicting treatment response to cognitive behavioral therapy in panic disorder with agoraphobia by integrating local neural information

T Hahn, T Kircher, B Straube, HU Wittchen… - JAMA …, 2015 - jamanetwork.com
Importance Although neuroimaging research has made substantial progress in identifying
the large-scale neural substrate of anxiety disorders, its value for clinical application lags …

Dysregulation of threat neurocircuitry during fear extinction: the role of anhedonia

KS Young, SY Bookheimer, R Nusslock… - …, 2021 - nature.com
Dimensional models of anxiety and depression highlight common and distinct symptom
clusters that are thought to reflect disruptions in underlying functional processes. The current …