Fluorescence imaging of large-scale neural ensemble dynamics

TH Kim, MJ Schnitzer - Cell, 2022 - cell.com
Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …

The role of GABAergic signalling in neurodevelopmental disorders

X Tang, R Jaenisch, M Sur - Nature Reviews Neuroscience, 2021 - nature.com
GABAergic inhibition shapes the connectivity, activity and plasticity of the brain. A series of
exciting new discoveries provides compelling evidence that disruptions in a number of key …

Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

KE Kishi, YS Kim, M Fukuda, M Inoue, T Kusakizako… - Cell, 2022 - cell.com
ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits
puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) …

Neural control of affiliative touch in prosocial interaction

YE Wu, J Dang, L Kingsbury, M Zhang, F Sun, RK Hu… - Nature, 2021 - nature.com
The ability to help and care for others fosters social cohesiveness and is vital to the physical
and emotional well-being of social species, including humans,–. Affiliative social touch, such …

POMC neuronal heterogeneity in energy balance and beyond: an integrated view

C Quarta, M Claret, LM Zeltser, KW Williams… - Nature …, 2021 - nature.com
Hypothalamic AgRP and POMC neurons are conventionally viewed as the yin and yang of
the body's energy status, since they act in an opposite manner to modulate appetite and …

Viral tools for neuroscience

AR Nectow, EJ Nestler - Nature Reviews Neuroscience, 2020 - nature.com
Recombinant viruses are the workhorse of modern neuroscience. Whether one would like to
understand a neuron's morphology, natural activity patterns, molecular composition …

Integrative neurocircuits that control metabolism and food intake

JC Brüning, H Fenselau - Science, 2023 - science.org
Systemic metabolism has to be constantly adjusted to the variance of food intake and even
be prepared for anticipated changes in nutrient availability. Therefore, the brain integrates …

[PDF][PDF] A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior

JR Knoedler, S Inoue, DW Bayless, T Yang, A Tantry… - Cell, 2022 - cell.com
Sex hormones exert a profound influence on gendered behaviors. How individual sex
hormone-responsive neuronal populations regulate diverse sex-typical behaviors is unclear …

The whisking oscillator circuit

J Takatoh, V Prevosto, PM Thompson, J Lu, L Chung… - Nature, 2022 - nature.com
Central oscillators are primordial neural circuits that generate and control rhythmic
movements,. Mechanistic understanding of these circuits requires genetic identification of …

Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility

CB Klune, B **, LA DeNardo - Elife, 2021 - elifesciences.org
The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …