The genetic architecture of repeated local adaptation to climate in distantly related plants

JR Whiting, TR Booker, C Rougeux, BM Lind… - Nature ecology & …, 2024 - nature.com
Closely related species often use the same genes to adapt to similar environments.
However, we know little about why such genes possess increased adaptive potential and …

The plant model system Arabidopsis set in an evolutionary, systematic, and spatio-temporal context

MA Koch - Journal of Experimental Botany, 2019 - academic.oup.com
Arabidopsis thaliana is one of the prevailing plant model systems used for most facets of
plant molecular, cell, and evolutionary biology. There are good reasons for that, such as …

Parallel adaptation in autopolyploid Arabidopsis arenosa is dominated by repeated recruitment of shared alleles

V Konečná, S Bray, J Vlček, M Bohutínská… - Nature …, 2021 - nature.com
Relative contributions of pre-existing vs de novo genomic variation to adaptation are poorly
understood, especially in polyploid organisms. We assess this in high resolution using …

Genomic Patterns of Local Adaptation under Gene Flow in Arabidopsis lyrata

T Hämälä, O Savolainen - Molecular Biology and Evolution, 2019 - academic.oup.com
Short-scale local adaptation is a complex process involving selection, migration, and drift.
The expected effects on the genome are well grounded in theory but examining these on an …

Transposable elements maintain genome-wide heterozygosity in inbred populations

H De Kort, S Legrand, O Honnay, J Buckley - Nature Communications, 2022 - nature.com
Elevated levels of inbreeding increase the risk of inbreeding depression and extinction, yet
many inbred species are widespread, suggesting that inbreeding has little impact on …

Local adaptation and ecological differentiation under selection, migration, and drift in Arabidopsis lyrata

T Hämälä, TM Mattila, O Savolainen - Evolution, 2018 - academic.oup.com
How the balance between selection, migration, and drift influences the evolution of local
adaptation has been under intense theoretical scrutiny. Yet, empirical studies that relate …

Polyploids broadly generate novel haplotypes from trans-specific variation in Arabidopsis arenosa and Arabidopsis lyrata

M Bohutínská, E Petříková, TR Booker… - PLoS …, 2024 - journals.plos.org
Polyploidy, the result of whole genome duplication (WGD), is widespread across the tree of
life and is often associated with speciation and adaptability. It is thought that adaptation in …

Environmental response in gene expression and DNA methylation reveals factors influencing the adaptive potential of Arabidopsis lyrata

T Hämälä, W Ning, H Kuittinen, N Aryamanesh… - ELife, 2022 - elifesciences.org
Understanding what factors influence plastic and genetic variation is valuable for predicting
how organisms respond to changes in the selective environment. Here, using gene …

Maintenance of adaptive dynamics and no detectable load in a range-edge outcrossing plant population

M Takou, T Hämälä, EM Koch, KA Steige… - Molecular Biology …, 2021 - academic.oup.com
During range expansion, edge populations are expected to face increased genetic drift,
which in turn can alter and potentially compromise adaptive dynamics, preventing the …

Biased Gene Conversion Constrains Adaptation in Arabidopsis thaliana

T Hämälä, P Tiffin - Genetics, 2020 - academic.oup.com
Reduction of fitness due to deleterious mutations imposes a limit to adaptive evolution. By
characterizing features that influence this genetic load we may better understand constraints …