[HTML][HTML] The extracellular matrix–immune microenvironment crosstalk in cancer therapy: challenges and opportunities

L Closset, O Gultekin, S Salehi, D Sarhan, K Lehti… - Matrix Biology, 2023 - Elsevier
Targeting the tumour immune microenvironment (TIME) by cancer immunotherapy has led to
improved patient outcomes. However, response to these treatments is heterogeneous and …

Inflammation of the pleural cavity: a review on pathogenesis, diagnosis and implications in tumor pathophysiology

G Karpathiou, M Péoc'h, A Sundaralingam, N Rahman… - Cancers, 2022 - mdpi.com
Simple Summary The pleura is a cavity whose pathology ranges from simple fluid
accumulation to tumor development, all inducing important consequences in patents health …

Exploration of multi-layered nanofiber adjuvant implants of doxorubicin and resveratrol to prevent post-surgery tumor recurrence and invasion

P Famta, S Shah, A Sharma, G Pandey… - Journal of Drug Delivery …, 2024 - Elsevier
Tumor-free survival post-surgical ablation is not durable due to tumor recurrence and
metastasis in breast cancer patients. Studies have reported that trauma-prone sites are most …

Simvastatin-loaded gelatin-capped polycaprolactone nanoparticles for the post-operative management of breast cancer

P Famta, S Shah, DA Srinivasarao, A Sharma… - Journal of Drug Delivery …, 2024 - Elsevier
Minimal residual disease at the tumor site after surgical ablation is a major cause for tumor
recurrence and metastasis. The tropism of circulating tumor cells towards injured areas …

Blood hypercoagulability and thrombosis mechanisms in cancer patients-A brief review

Q Peng, J Zhu, Y Zhang, Y **g - Heliyon, 2024 - cell.com
Patients with malignant tumors are prone to present hypercoagulability of blood and form
thrombosis, and its pathogenesis is complex involving various factors from clinical and …

A human ex vivo coculture model to investigate peritoneal metastasis and innovative treatment options

D Mönch, J Koch, A Maaß, N Janssen… - Pleura and …, 2021 - degruyter.com
Objectives Peritoneal metastasis (PM) is commonly observed in patients with colorectal
cancer (CRC). The outcome of these patients is poor, with an average survival of only six …

Use of early postoperative intraperitoneal 5‐fluorouracil with index cytoreduction improves survival with secondary cytoreductive surgery

PH Sugarbaker, D Chang - Journal of Surgical Oncology, 2024 - Wiley Online Library
Background In patients with appendiceal mucinous neoplasm with peritoneal dissemination,
a cytoreductive surgery (CRS) with perioperative chemotherapy may result in long‐term …

Blood Clot Dynamics and Fibrinolysis Impairment in Cancer: The Role of Plasma Histones and DNA

M Ullah, S Mirshahi, A Valinattaj Omran, I Aldybiat… - Cancers, 2024 - mdpi.com
Simple Summary Blood clots are formed when blood vessels are injured. They help stop
bleeding and heal wounds, but can also cause serious problems if they block blood flow or …

Critical reappraisal of prognostic indicators for 949 mucinous appendiceal neoplasm patients

PH Sugarbaker, D Chang - Journal of Surgical Oncology, 2024 - Wiley Online Library
Abstract Background and Objectives The standard of care for treatment of an appendiceal
mucinous neoplasm with peritoneal dissemination is cytoreductive surgery (CRS) combined …

Experimental evaluation of icodextrin delivery as pressurized aerosol (PIPAC): Antiadhesive and cytotoxic effects

HS Keck, FJ Weinreich, R Shegokar… - European Journal of …, 2021 - Elsevier
Background Icodextrin (IDX) is an antiadhesive polymer that can be used as a carrier
solution for intraperitoneal (IP) delivery of chemotherapeutic drugs. Methods We …