A review of heterogeneity in attention deficit/hyperactivity disorder (ADHD)
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that affects
approximately 8%–12% of children worldwide. Throughout an individual's lifetime, ADHD …
approximately 8%–12% of children worldwide. Throughout an individual's lifetime, ADHD …
Unity and diversity of executive functions: Individual differences as a window on cognitive structure
Executive functions (EFs) are high-level cognitive processes, often associated with the
frontal lobes, that control lower level processes in the service of goal-directed behavior …
frontal lobes, that control lower level processes in the service of goal-directed behavior …
Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories
CC Gross, A Schulte-Mecklenbeck… - Science Translational …, 2024 - science.org
One of the biggest challenges in managing multiple sclerosis is the heterogeneity of clinical
manifestations and progression trajectories. It still remains to be elucidated whether this …
manifestations and progression trajectories. It still remains to be elucidated whether this …
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
Three Approaches to Understanding and Classifying Mental Disorder: ICD-11, DSM-5, and the National Institute of Mental Health's Research Domain Criteria (RDoC)
LA Clark, B Cuthbert… - … Science in the …, 2017 - journals.sagepub.com
The diagnosis of mental disorder initially appears relatively straightforward: Patients present
with symptoms or visible signs of illness; health professionals make diagnoses based …
with symptoms or visible signs of illness; health professionals make diagnoses based …
Genetic insights into the neurodevelopmental origins of schizophrenia
R Birnbaum, DR Weinberger - Nature Reviews Neuroscience, 2017 - nature.com
Schizophrenia is a severe neuropsychiatric disorder with a longstanding history of
neurobiological investigation. Although the underlying causal mechanisms remain …
neurobiological investigation. Although the underlying causal mechanisms remain …
Executive function in autism spectrum disorder: history, theoretical models, empirical findings, and potential as an endophenotype
This review presents an outline of executive function (EF) and its application to autism
spectrum disorder (ASD). The development of the EF construct, theoretical models of EF …
spectrum disorder (ASD). The development of the EF construct, theoretical models of EF …
Painful temporomandibular disorder: decade of discovery from OPPERA studies
GD Slade, R Ohrbach, JD Greenspan… - Journal of dental …, 2016 - journals.sagepub.com
In 2006, the OPPERA project (Orofacial Pain: Prospective Evaluation and Risk Assessment)
set out to identify risk factors for development of painful temporomandibular disorder (TMD) …
set out to identify risk factors for development of painful temporomandibular disorder (TMD) …
Social cognition in schizophrenia
Individuals with schizophrenia exhibit impaired social cognition, which manifests as
difficulties in identifying emotions, feeing connected to others, inferring people's thoughts …
difficulties in identifying emotions, feeing connected to others, inferring people's thoughts …
Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics
AM Buch, C Liston - Neuropsychopharmacology, 2021 - nature.com
Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …