MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance

MA Iqbal, S Arora, G Prakasam, GA Calin… - Molecular aspects of …, 2019 - Elsevier
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

The regulatory role of micro RNA s in angiogenesis‐related diseases

LL Sun, WD Li, FR Lei, XQ Li - Journal Of Cellular And …, 2018 - Wiley Online Library
Micro RNA s (mi RNA s) are small non‐coding RNA s that regulate gene expression at a
post‐transcriptional level via either the degradation or translational repression of a target …

A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer

M Hanke, K Hoefig, H Merz, AC Feller, I Kausch… - … oncology: seminars and …, 2010 - Elsevier
OBJECTIVES: MicroRNAs have been shown to be related to specific types of malignant cell
growth. In case of urothelial bladder cancer (BCa), novel noninvasive diagnosis is …

MicroRNAs—the micro steering wheel of tumour metastases

MS Nicoloso, R Spizzo, M Shimizu, S Rossi… - Nature Reviews …, 2009 - nature.com
Recently, microRNAs (miRNAs) have been discovered to have a role in metastasis. Here we
describe how miRNAs are involved in advanced stages of tumour progression, stressing …

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis

Y Zhang, P Yang, T Sun, D Li, X Xu, Y Rui, C Li… - Nature cell …, 2013 - nature.com
The tumour stroma is an active participant during cancer progression. Stromal cells promote
tumour progression and metastasis through multiple mechanisms including enhancing …

[HTML][HTML] MicroRNA regulatory networks in cardiovascular development

N Liu, EN Olson - Developmental cell, 2010 - cell.com
The heart, more than any other organ, requires precise functionality on a second-to-second
basis throughout the lifespan of the organism. Even subtle perturbations in cardiac structure …

A serum circulating miRNA diagnostic test to identify asymptomatic high‐risk individuals with early stage lung cancer

F Bianchi, F Nicassio, M Marzi, E Belloni… - EMBO molecular …, 2011 - embopress.org
Lung cancer is the first cause of cancer mortality worldwide, and its early detection is
currently the main available strategy to improve disease prognosis. While early diagnosis …

MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor

J Tie, Y Pan, L Zhao, K Wu, J Liu, S Sun, X Guo… - PLoS …, 2010 - journals.plos.org
MicroRNAs play key roles in tumor metastasis. Here, we describe the regulation and
function of miR-218 in gastric cancer (GC) metastasis. miR-218 expression is decreased …

MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells

J Godlewski, MO Nowicki, A Bronisz, G Nuovo… - Molecular cell, 2010 - cell.com
To sustain tumor growth, cancer cells must be able to adapt to fluctuations in energy
availability. We have identified a single microRNA that controls glioma cell proliferation …