An ecotoxicological view on neurotoxicity assessment

JB Legradi, C Di Paolo, MHS Kraak… - Environmental Sciences …, 2018 - Springer
The numbers of potential neurotoxicants in the environment are raising and pose a great risk
for humans and the environment. Currently neurotoxicity assessment is mostly performed to …

Odor coding in the mammalian olfactory epithelium

SM Kurian, RG Naressi, D Manoel, AS Barwich… - Cell and Tissue …, 2021 - Springer
Noses are extremely sophisticated chemical detectors allowing animals to use scents to
interpret and navigate their environments. Odor detection starts with the activation of odorant …

The Ensembl gene annotation system

BL Aken, S Ayling, D Barrell, L Clarke, V Curwen… - Database, 2016 - academic.oup.com
The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …

Hierarchical deconstruction of mouse olfactory sensory neurons: from whole mucosa to single-cell RNA-seq

LR Saraiva, X Ibarra-Soria, M Khan, M Omura… - Scientific reports, 2015 - nature.com
The mouse olfactory mucosa is a complex chemosensory tissue composed of multiple cell
types, neuronal and non-neuronal. We have here applied RNA-seq hierarchically, in three …

The evolving neural and genetic architecture of vertebrate olfaction

DM Bear, JM Lassance, HE Hoekstra, SR Datta - Current Biology, 2016 - cell.com
Evolution sculpts the olfactory nervous system in response to the unique sensory challenges
facing each species. In vertebrates, dramatic and diverse adaptations to the chemical …

Intranasal delivery of SARS-CoV-2 spike protein is sufficient to cause olfactory damage, inflammation and olfactory dysfunction in zebrafish

A Kraus, M Huertas, L Ellis, P Boudinot… - Brain, behavior, and …, 2022 - Elsevier
Anosmia, loss of smell, is a prevalent symptom of SARS-CoV-2 infection. Anosmia may be
explained by several mechanisms driven by infection of non-neuronal cells and damage in …

The olfactory system of zebrafish as a model for the study of neurotoxicity and injury: implications for neuroplasticity and disease

E Calvo-Ochoa, CA Byrd-Jacobs - International journal of molecular …, 2019 - mdpi.com
The olfactory system, composed of the olfactory organs and the olfactory bulb, allows
organisms to interact with their environment and through the detection of odor signals …

[HTML][HTML] Pheromone sensing in mammals: a review of the vomeronasal system

MV Torres, I Ortiz-Leal, P Sanchez-Quinteiro - Anatomia, 2023 - mdpi.com
This review addresses the role of chemical communication in mammals, giving special
attention to the vomeronasal system in pheromone-mediated interactions. The vomeronasal …

A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans

LR Saraiva, F Riveros-McKay, M Mezzavilla… - Science …, 2019 - science.org
The mammalian olfactory system displays species-specific adaptations to different
ecological niches. To investigate the evolutionary dynamics of olfactory sensory neuron …

A 3D transcriptomics atlas of the mouse nose sheds light on the anatomical logic of smell

MLRT Segura, E Abou Moussa, E Garabello… - Cell Reports, 2022 - cell.com
The sense of smell helps us navigate the environment, but its molecular architecture and
underlying logic remain understudied. The spatial location of odorant receptor genes (Olfrs) …