Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty
Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
[HTML][HTML] BRCA genes: the role in genome stability, cancer stemness and therapy resistance
Carcinogenesis is a multistep process, and tumors frequently harbor multiple mutations
regulating genome integrity, cell division and death. The integrity of cellular genome is …
regulating genome integrity, cell division and death. The integrity of cellular genome is …
HOTAIR: a potential metastatic, drug-resistant and prognostic regulator of breast cancer
HOX transcript antisense intergenic RNA (HOTAIR) is an oncogenic non-coding RNA whose
expression is strongly correlated with the tumor grade and prognosis of a variety of …
expression is strongly correlated with the tumor grade and prognosis of a variety of …
LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer
A Bhan, SS Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Non-coding RNAs (ncRNAs) are emerging classes of regulatory RNA that play key roles in
various cellular and physiological processes such as in gene regulation, chromatin …
various cellular and physiological processes such as in gene regulation, chromatin …
HOTAIR: an oncogenic long non-coding RNA in human cancer
Q Tang, SS Hann - Cellular Physiology and Biochemistry, 2018 - karger.com
Abstract Long non-coding RNAs (LncRNAs) represent a novel class of noncoding RNAs that
are longer than 200 nucleotides without protein-coding potential and function as novel …
are longer than 200 nucleotides without protein-coding potential and function as novel …
Functions of lncRNA HOTAIR in lung cancer
G Loewen, J Jayawickramarajah, Y Zhuo… - Journal of hematology & …, 2014 - Springer
Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes.
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
HOTAIR LncRNA: a novel oncogenic propellant in human cancer
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …
[HTML][HTML] A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling
Summary N 6-methyladenosine (m 6 A) of mRNAs modulated by the METTL3-METTL14-
WTAP-RBM15 methyltransferase complex and m 6 A demethylases such as FTO play …
WTAP-RBM15 methyltransferase complex and m 6 A demethylases such as FTO play …
Going beyond Polycomb: EZH2 functions in prostate cancer
Abstract The Polycomb group (PcG) protein Enhancer of Zeste Homolog 2 (EZH2) is one of
the three core subunits of the Polycomb Repressive Complex 2 (PRC2). It harbors histone …
the three core subunits of the Polycomb Repressive Complex 2 (PRC2). It harbors histone …
HOX transcript antisense RNA (HOTAIR) in cancer
X Qu, S Alsager, Y Zhuo, B Shan - Cancer letters, 2019 - Elsevier
Long noncoding RNAs (lncRNAs) have emerged as a new family of master regulators of
cancer. The lncRNA HOX transcript antisense RNA (HOTAIR) is a prime example of an …
cancer. The lncRNA HOX transcript antisense RNA (HOTAIR) is a prime example of an …