Liposomes have been considered promising and versatile drug vesicles. Compared with
traditional drug delivery systems, liposomes exhibit better properties, including site …

The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …

Interleukin-11 (IL-11) is a profibrotic cytokine essential for the differentiation of fibroblasts
into collagen-secreting, actin alpha 2, smooth muscle–positive (ACTA2+) myofibroblasts …

Ionizable cationic lipid-containing lipid nanoparticles (LNPs) are the most clinically
advanced non-viral gene delivery platforms, holding great potential for gene therapeutics …

The unique natural advantages of polysaccharide materials have attracted attention in
biomedical applications. The abundant modifiable functional groups on the polysaccharide …

In the field of targeted drug delivery, the effects of size and morphology of drug nanocarriers
are of great importance and need to be discussed in depth. To be concise, among all the …

Chronic liver injury and inflammation triggered by metabolic abnormalities initiate the
activation of hepatic stellate cells (HSCs), driving fibrosis and parenchymal dysfunction …

Gene therapy is a promising approach for the treatment of several diseases, such as chronic
or viral infections, inherited disorders, and cancer. The cellular internalization of exogenous …

Autoimmune diseases are a group of serious immune system disorders that are usually
idiopathic and persistent. Currently, autoimmune diseases are often diagnosed after obvious …

Cardiovascular diseases, such as myocardial infarction (MI), are a leading cause of death
worldwide. Acute MI (AMI) inflicts massive injury to the coronary microcirculation, causing …