[HTML][HTML] Cytochrome P450: polymorphisms and roles in cancer, diabetes and atherosclerosis
Cytochromes P450s (CYPs) constitute a superfamily of enzymes that catalyze the
metabolism of drugs and other substances. Endogenous substrates of CYPs include …
metabolism of drugs and other substances. Endogenous substrates of CYPs include …
Effect of caffeine consumption on the risk for neurological and psychiatric disorders: sex differences in human
HJ Jee, SG Lee, KJ Bormate, YS Jung - Nutrients, 2020 - mdpi.com
Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been
used safely as a mild stimulant for a long time. However, excessive caffeine consumption …
used safely as a mild stimulant for a long time. However, excessive caffeine consumption …
Cytochrome P450 2D6 and Parkinson's disease: polymorphism, metabolic role, risk and protection
MS ur Rasheed, AK Mishra, MP Singh - Neurochemical Research, 2017 - Springer
Abstract Cytochrome P450 (CYP) 2D6 is one of the most highly active, oxidative and
polymorphic enzymes known to metabolize Parkinsonian toxins and clinically established …
polymorphic enzymes known to metabolize Parkinsonian toxins and clinically established …
A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson's disease
P Hartz, T Fehlmann, G Wagenpfeil… - Frontiers in …, 2023 - frontiersin.org
Genetic and environmental factors lead to the manifestation of Parkinson's disease (PD) but
related mechanisms are only rudimentarily understood. Cytochromes P450 (P450s) are …
related mechanisms are only rudimentarily understood. Cytochromes P450 (P450s) are …
Neuroprotection or neurotoxicity of illicit drugs on Parkinson's disease
Parkinson's Disease (PD) is currently the most rapid growing neurodegenerative disease
and over the past generation, its global burden has more than doubled. The onset of PD can …
and over the past generation, its global burden has more than doubled. The onset of PD can …
Cytochrome P450 enzymes and metabolism of drugs and neurotoxins within the mammalian brain
MR Stocco, RF Tyndale - Advances in Pharmacology, 2022 - Elsevier
Cytochrome P450 enzymes (CYPs) that metabolize xenobiotics are expressed and active in
the brain. These CYPs contribute to the metabolism of many centrally acting compounds …
the brain. These CYPs contribute to the metabolism of many centrally acting compounds …
A General Protocol for Cu-Mediated Fluoro-deamination: Sandmeyer Fluorination of Diverse Aromatic Substrates
RM Perez-Garcia, G Grønnevik, PJ Riss - Organic Letters, 2021 - ACS Publications
A Cu (I)-mediated fluoro-deamination method for nucleophilic radiofluorination was devised.
The method affords fluorinated aromatic products directly from anilines under both no-carrier …
The method affords fluorinated aromatic products directly from anilines under both no-carrier …