Sex disparities matter in cancer development and therapy
Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …
molecular and genomic therapies. Currently, whether patients with non-reproductive …
[HTML][HTML] Chemical constituents of Panax ginseng and Panax notoginseng explain why they differ in therapeutic efficacy
H Liu, X Lu, Y Hu, X Fan - Pharmacological research, 2020 - Elsevier
Abstract Panax ginseng (Meyer) and Panax notoginseng (Burkill), belonging to the family
Araliaceae, are used worldwide as medicinal and functional herbs. Numerous publications …
Araliaceae, are used worldwide as medicinal and functional herbs. Numerous publications …
Toll-like receptors in immunity and inflammatory diseases: Past, present, and future
K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …
cope with various pathogens present in the vicinity of environmental surroundings inhabited …
Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2
AS Wilson, KL Randall, JA Pettitt, JI Ellyard… - Nature …, 2022 - nature.com
Neutrophils perform critical functions in the innate response to infection, including through
the production of neutrophil extracellular traps (NETs)-web-like DNA structures which are …
the production of neutrophil extracellular traps (NETs)-web-like DNA structures which are …
The interferon (IFN) class of cytokines and the IFN regulatory factor (IRF) transcription factor family
H Negishi, T Taniguchi, H Yanai - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Interferons (IFNs) are a broad class of cytokines elicited on challenge to the host defense
and are essential for mobilizing immune responses to pathogens. Divided into three classes …
and are essential for mobilizing immune responses to pathogens. Divided into three classes …
[HTML][HTML] Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases
Panax ginseng is one of the most universally used herbal medicines in Asian and Western
countries. Most of the biological activities of ginseng are derived from its main constituents …
countries. Most of the biological activities of ginseng are derived from its main constituents …
The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …
Immune sensing mechanisms that discriminate self from altered self and foreign nucleic acids
All lifeforms have developed highly sophisticated systems equipped to detect altered self
and non-self nucleic acids (NA). In vertebrates, NA-sensing receptors safeguard the integrity …
and non-self nucleic acids (NA). In vertebrates, NA-sensing receptors safeguard the integrity …
Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines
Toll-like receptors (TLRs) are transmembrane proteins belonging to the family of pattern-
recognition receptors. They function as sensors of invading pathogens through recognition …
recognition receptors. They function as sensors of invading pathogens through recognition …
A comparative review of toll-like receptor 4 expression and functionality in different animal species
C Vaure, Y Liu - Frontiers in immunology, 2014 - frontiersin.org
Toll-like receptors (TLRs) belong to the pattern recognition receptor (PRR) family, a key
component of the innate immune system. TLRs detect invading pathogens and initiate an …
component of the innate immune system. TLRs detect invading pathogens and initiate an …