Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …

Since the first genome-scale comparisons, it has been evident that the genomes of many
species are unbound by strict vertical descent: Large differences in gene content can occur …

Bacteriophages have important roles in the ecology of the human gut microbiome but are
under-represented in reference databases. To address this problem, we assembled the …

Millions of new viral sequences have been identified from metagenomes, but the quality and
completeness of these sequences vary considerably. Here we present CheckV, an …

INTRODUCTION Microbial populations display heterogeneous gene expression profiles that
result in phenotypic differences between individual bacteria. This diversity can allow …

Abstract PHASTEST (PHAge Search Tool with Enhanced Sequence Translation) is the
successor to the PHAST and PHASTER prophage finding web servers. PHASTEST is …

Phages and plasmids are regarded as distinct types of mobile genetic elements that drive
bacterial evolution by horizontal gene transfer. However, the distinction between both types …

Many bacteria produce extracellular and surface-associated components such as
membrane vesicles (MVs), extracellular DNA and moonlighting cytosolic proteins for which …

Prokaryotes have numerous mobile genetic elements (MGEs) that mediate horizontal gene
transfer (HGT) between cells. These elements can be costly, even deadly, and cells use …

Antibiotic resistance is rapidly spreading via the horizontal transfer of resistance genes in
mobile genetic elements. While plasmids are key drivers of this process, few integrative …