Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

The olfactory neuroepithelium undergoes continual neurogenesis and, after extensive
lesions, fully regenerates to maintain sensory function. The stem cell population underlying …

In the olfactory epithelium (OE), generation of new neurons by neuronal progenitors is
inhibited by a signal from neurons themselves. Here we provide evidence that this feedback …

It is widely accepted that the growth and regeneration of tissues and organs is tightly
controlled. Although experimental studies are beginning to reveal molecular mechanisms …

Signaling by the transforming growth factor β (TGF-β) family is necessary for proper neural
development and function throughout life. Sequential waves of activation, inhibition, and …

The sensory neurons that subserve olfaction, olfactory receptor neurons (ORNs), are
regenerated throughout life, making the neuroepithelium in which they reside [the olfactory …

The limbic system of the brain regulates a number of behaviors that are essential for the
survival of all vertebrate species including humans. The limbic system predominantly …

We describe a distinctive, widespread population of neurons situated beneath the pial
surface of the human embryonic forebrain even before complete closure of the neural tube …

The mammalian olfactory neuroepithelium provides a unique system for understanding the
regulation of neurogenesis by adult neural stem cells. Recently, mouse horizontal basal …