Unraveling the Complex Interconnection between Specific Inflammatory Signaling Pathways and Mechanisms Involved in HIV-Associated Colorectal Oncogenesis

BP Damane, TV Mulaudzi, SS Kader, P Naidoo… - Cancers, 2023 - mdpi.com
Simple Summary Despite the reduced death rate that comes with improved HIV treatment,
chances of develo** cancers in HIV infected individuals remains high. The main culprit …

Host cell glycosylation selects for infection with CCR5-versus CXCR4-tropic HIV-1

HL Itell, J Guenthoer, D Humes, NE Baumgarten… - Nature …, 2024 - nature.com
Human immunodeficiency virus type 1 (HIV-1) infection involves a selection bottleneck that
leads to transmission of one or a few variants. C–C motif chemokine receptor 5 (CCR5) or C …

[HTML][HTML] Amino acid substitution of the membrane-proximal external region alter neutralization sensitivity in a chronic HIV-1 clade B infected patient

Y Fu, S Wang, Y Hao, D Li, L Ren, Z Wang, R Chen… - Virus Research, 2024 - Elsevier
The membrane-proximal external region (MPER) represents a highly conserved region of
the Human Immunodeficiency Virus (HIV) envelope glycoprotein (env) targeted by several …

[PDF][PDF] Unraveling the Complex Interconnection Between Specific Inflammatory Signaling Pathways and Mechanisms Involved in HIV-Associated Colorectal …

BP Damane, TV Mulaudzi, SS Kader, P Naidoo… - 2023 - researchgate.net
The advancement of HIV treatment has led to increased life expectancy. However, people
living with HIV (PLWH) are at a higher risk of develo** colorectal cancers. Chronic …

Identifying host factors that inhibit HIV-1 infection in primary CD4+ T cells

HL Itell - 2023 - search.proquest.com
Cellular antiviral factors comprise one of the first lines of defense against viral infection. In
the case of HIV-1, it is well established that the early stages of natural infection are …

[KNIHA][B] Modeling the HIV Genetic Bottleneck in vitro

TA Caldwell III - 2023 - search.proquest.com
As of the year 2023, there has yet to be developed an effective prophylactic vaccine against
HIV-1 infection. One likely reason for prior failures in vaccine trials is that vaccines have …