Advances in the science and treatment of alcohol use disorder

K Witkiewitz, RZ Litten, L Leggio - Science advances, 2019 - science.org
Alcohol is a major contributor to global disease and a leading cause of preventable death,
causing approximately 88,000 deaths annually in the United States alone. Alcohol use …

The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex

AO Ceceli, CW Bradberry, RZ Goldstein - Neuropsychopharmacology, 2022 - nature.com
A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

Brain lesions disrupting addiction map to a common human brain circuit

J Joutsa, K Moussawi, SH Siddiqi, A Abdolahi… - Nature medicine, 2022 - nature.com
Drug addiction is a public health crisis for which new treatments are urgently needed. In rare
cases, regional brain damage can lead to addiction remission. These cases may be used to …

Transcranial magnetic stimulation, deep brain stimulation, and other forms of neuromodulation for substance use disorders: Review of modalities and implications for …

JJ Mahoney III, CA Hanlon, PJ Marshalek… - Journal of the …, 2020 - Elsevier
Given the high prevalence of individuals diagnosed with substance use disorder, along with
the elevated rate of relapse following treatment initiation, investigating novel approaches …

Deep brain stimulation of the nucleus accumbens in treatment-resistant alcohol use disorder: a double-blind randomized controlled multi-center trial

P Bach, M Luderer, UJ Müller, M Jakobs… - Translational …, 2023 - nature.com
Abstract Treatment resistance in alcohol use disorders (AUD) is a major problem for affected
individuals and for society. In the search of new treatment options, few case studies using …

A roadmap for integrating neuroscience into addiction treatment: a consensus of the neuroscience interest group of the international society of addiction medicine

A Verdejo-Garcia, V Lorenzetti, V Manning… - Frontiers in …, 2019 - frontiersin.org
Although there is general consensus that altered brain structure and function underpins
addictive disorders, clinicians working in addiction treatment rarely incorporate …

[HTML][HTML] Targeting cravings in substance addiction with transcranial direct current stimulation: insights from a meta-analysis of sham-controlled trials

YH Chan, HM Chang, ML Lu, KK Goh - Psychiatry research, 2024 - Elsevier
Addiction is a substantial health concern; craving—the core symptom of addiction—is
strongly associated with relapse. Transcranial direct current stimulation (tDCS) is a …

Drug addiction: from bench to bedside

J Cheron, A Kerchove d'Exaerde - Translational Psychiatry, 2021 - nature.com
Drug addiction is responsible for millions of deaths per year around the world. Still, its
management as a chronic disease is shadowed by misconceptions from the general public …

[HTML][HTML] Transcranial direct current stimulation combined with alcohol cue inhibitory control training reduces the risk of early alcohol relapse: a randomized placebo …

M Dubuson, C Kornreich, MA Vanderhasselt, C Baeken… - Brain Stimulation, 2021 - Elsevier
Background Approximately half of all people with alcohol use disorder (AUD) relapse into
alcohol reuse in the next few weeks after a withdrawal treatment. Brain stimulation and …

What Chemsex does to the brain-neural correlates (ERP) regarding decision making, impulsivity and hypersexuality

J Schwarz, M Gertzen, A Rabenstein… - European Archives of …, 2024 - Springer
Chemsex describes the use of specific substances (methamphetamine, GHB/GBL,
mephedrone, ketamine) which initiate or enhance sexual experiences and is mainly …