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[HTML][HTML] Chronic inflammation and the hallmarks of aging
Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …
Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
[کتاب][B] Examining illiberal trends and anti-EU politics in east Central Europe from a domestic perspective: State of research and outline of the book
LH Anders, A Lorenz - 2021 - library.oapen.org
In East Central Europe (ECE), democracy and the rule of law are under siege, most notably
in Hungary and Poland and, to a lesser extent, also in the Czech Republic and Slovakia …
in Hungary and Poland and, to a lesser extent, also in the Czech Republic and Slovakia …
Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments
Extracellular communication, in other words, crosstalk between cells, has a pivotal role in
the survival of an organism. This communication occurs by different methods, one of which is …
the survival of an organism. This communication occurs by different methods, one of which is …
Plasmacytoid dendritic cells: development, regulation, and function
B Reizis - Immunity, 2019 - cell.com
Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-
derived nucleic acids and respond with rapid and massive production of type I interferon …
derived nucleic acids and respond with rapid and massive production of type I interferon …
The tRNAVal half: A strong endogenous Toll-like receptor 7 ligand with a 5′-terminal universal sequence signature
Toll-like receptors (TLRs) are crucial components of the innate immune system. Endosomal
TLR7 recognizes single-stranded RNAs, yet its endogenous ssRNA ligands are not fully …
TLR7 recognizes single-stranded RNAs, yet its endogenous ssRNA ligands are not fully …
SARS-CoV-2–associated ssRNAs activate inflammation and immunity via TLR7/8
The inflammatory and IFN pathways of innate immunity play a key role in the resistance and
pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors and SARS-CoV-2 …
pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors and SARS-CoV-2 …
Exosomes: The emerging mechanisms and potential clinical applications in dermatology
H Yu, H Feng, H Zeng, Y Wu, Q Zhang… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Skin tissue, composed of epidermis, dermis, and subcutaneous tissue, is the largest organ of
the human body. It serves as a protective barrier against pathogens and physical trauma …
the human body. It serves as a protective barrier against pathogens and physical trauma …
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis
Z Ni, L Kuang, H Chen, Y **e, B Zhang, J Ouyang… - Cell death & …, 2019 - nature.com
Synovitis, a common clinical symptom for osteoarthritis (OA) patients, is highly related to OA
pathological progression and pain manifestation. The activated synovial macrophages have …
pathological progression and pain manifestation. The activated synovial macrophages have …
[HTML][HTML] DC-based vaccines for cancer immunotherapy
As the sentinels of the immune system, dendritic cells (DCs) play a critical role in initiating
and regulating antigen-specific immune responses. Cross-priming, a process that DCs …
and regulating antigen-specific immune responses. Cross-priming, a process that DCs …