Redox control of calcium channels: from mechanisms to therapeutic opportunities

LC Hool, B Corry - Antioxidants and Redox Signaling, 2007 - liebertpub.com
Calcium plays an integral role in cellular function. It is a well-recognized second messenger
necessary for signaling cellular responses, but in excessive amounts can be deleterious to …

Hypoxia-induced changes in neuronal network properties

F Peña, JM Ramirez - Molecular neurobiology, 2005 - Springer
Because of their high energetic demand, neurons within the mammalian central nervous
system are extremely sensitive to changes in partial pressure of oxygen. Faced with acute …

The effect of cerium dioxide nanoparticles on the viability of hippocampal neurons in Alzheimer's disease modeling

VV Hanzha, NM Rozumna, YV Kravenska… - Frontiers in Cellular …, 2023 - frontiersin.org
The possibilities of using nanoparticle materials based on cerium dioxide (CNPs) are
exciting since they are low toxic and have specific redox, antiradical properties. It can be …

The effects of short-term hypoxia on motor cortex excitability and neuromuscular activation

C Szubski, M Burtscher… - Journal of Applied …, 2006 - journals.physiology.org
The effects of acute hypoxia on motor cortex excitability, force production, and voluntary
activation were studied using single-and double-pulse transcranial magnetic stimulation …

Expression of Regucalcin, a calcium-binding protein is regulated by hypoxia-inducible factor-1α

T Singh, P Banerjee, S Kumari, A Chopra, N Singh… - Life Sciences, 2022 - Elsevier
Regucalcin (RGN) regulates intracellular Ca 2+ homeostasis and the activity of several
proteins involved in intracellular signaling pathways, which highlights its importance in cell …

[HTML][HTML] Action of hypoxia on different types of calcium channels in hippocampal neurons

EA Lukyanetz, VM Shkryl, OV Kravchuk… - Biochimica et Biophysica …, 2003 - Elsevier
Whole-cell patch clamp and polarographic oxygen partial pressure (pO2) measurements
were used to establish the sensitivity of high-voltage-activated (HVA) Ca2+ channel …

Effect of cyclosporin A on the viability of hippocampal cells cultured under conditions of modeling of Alzheimer's disease

EV Kravenska, VV Ganzha, EN Yavorskaya… - Neurophysiology, 2016 - Springer
The presence of amyloid plaques and neurofibrillary tangles accompanied by
manifestations of intense neurodegeneration in the brain is the main syndrome of …

Oxygen sensor of the heart

JC Fernández-Morales, M Morad - Canadian Journal of …, 2022 - cdnsciencepub.com
How oxygen is sensed by the heart and what mechanisms mediate its sensing remain
poorly understood. As recent reports show that low PO2 levels are detected by the …

Inhibition of high-voltage-activated calcium currents by acute hypoxia in cultured retinal ganglion cells

H Dumanska, M Telka, N Veselovsky - Frontiers in Cellular …, 2023 - frontiersin.org
Hypoxia is a common factor of numerous ocular diseases that lead to dysfunctions and loss
of retinal ganglion cells (RGCs) with subsequent vision loss. High-voltage-activated calcium …

Mechanism of Ca2+/calmodulin-dependent protein kinase IV activation and of cyclic AMP response element binding protein phosphorylation during hypoxia in the …

K Hornick, E Chang, AB Zubrow, OP Mishra… - Brain research, 2007 - Elsevier
Previously we showed that hypoxia results in increased neuronal nuclear Ca2+ influx,
Ca2+/calmodulin-dependent protein kinase IV activity (CaM KIV) and phosphorylation of c …