Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …
Biochanin A: A novel bioactive multifunctional compound from nature
Natural products (NPs) will continue to serve humans as matchless source of novel drug
leads and an inspiration for the synthesis of non-natural drugs. As our scientific …
leads and an inspiration for the synthesis of non-natural drugs. As our scientific …
Targeting apoptosis pathways in cancer and perspectives with natural compounds from mother nature
Although the incidences are increasing day after day, scientists and researchers taken
individually or by research group are trying to fight against cancer by several ways and also …
individually or by research group are trying to fight against cancer by several ways and also …
Applications of sesquiterpene lactones: a review of some potential success cases
L Moujir, O Callies, PMC Sousa, F Sharopov… - Applied Sciences, 2020 - mdpi.com
Sesquiterpene lactones, a vast range of terpenoids isolated from Asteraceae species,
exhibit a broad spectrum of biological effects and several of them are already commercially …
exhibit a broad spectrum of biological effects and several of them are already commercially …
Nanoformulated codelivery of quercetin and alantolactone promotes an antitumor response through synergistic immunogenic cell death for microsatellite-stable …
Microsatellite-stable colorectal cancer (CRC) is known to be resistant to immunotherapy.
The combination of quercetin (Q) and alantolactone (A) was found to induce synergistic …
The combination of quercetin (Q) and alantolactone (A) was found to induce synergistic …
Exploring the recent trends in perturbing the cellular signaling pathways in cancer by natural products
Cancer is commonly thought to be the product of irregular cell division. According to the
World Health Organization (WHO), cancer is the major cause of death globally. Nature offers …
World Health Organization (WHO), cancer is the major cause of death globally. Nature offers …
[HTML][HTML] Curcumol: from plant roots to cancer roots
Natural products, an infinite treasure of bioactive scaffolds, have provided an excellent
reservoir for the discovery of drugs since millennium. These naturally occurring, biologically …
reservoir for the discovery of drugs since millennium. These naturally occurring, biologically …
Back to the roots—an overview of the chemical composition and bioactivity of selected root-essential oils
K Lunz, I Stappen - Molecules, 2021 - mdpi.com
Since ancient times, plant roots have been widely used in traditional medicine for treating
various ailments and diseases due to their beneficial effects. A large number of studies have …
various ailments and diseases due to their beneficial effects. A large number of studies have …
Natural products against cancer angiogenesis
The process of angiogenesis is quite well-known nowadays. Some medicines and extracts
affecting this process are already used routinely in supporting the conventional treatment of …
affecting this process are already used routinely in supporting the conventional treatment of …
Sesquiterpene lactones as promising candidates for cancer therapy: Focus on pancreatic cancer
LC Laurella, NT Mirakian, MN Garcia, DH Grasso… - Molecules, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease which confers to
patients a poor prognosis at short term. PDAC is the fourth leading cause of death among …
patients a poor prognosis at short term. PDAC is the fourth leading cause of death among …