Owing to the small quantities of analytes and small volumes involved in single-cell analysis
techniques, manipulation strategies must be chosen carefully. The lysis of single cells for …

Single cell analysis is the measurement of transcription, translation, regulatory, and
signaling events within individual cells at the molecular level. The goal is to analyze and …

For over a century, enzymatic activity has been studied in vitro, assuming similar activity in
the crowded cellular milieu. Here, we determined in real time the catalytic activity of TEM1-β …

Seemingly identical cells can differ in their biochemical state, function and fate, and this
variability plays an increasingly recognized role in organism-level outcomes. Cellular …

This review focuses on the period from January 2004 to December 2005. Nearly 5000
papers and 500 reviews on capillary electrophoresis are listed in SciFinder for this period …

Cells are the fundamental unit of life, and studies on cell contribute to reveal the mystery of
life. However, since variability exists between individual cells even in the same kind of cells …

The rapid development of next-generation sequencing techniques has enabled single-cell
genomic and transcriptomic analyses, which have revealed the importance of heterogeneity …

Chemical analysis of single cells requires methods for quickly and quantitatively detecting a
diverse array of analytes from extremely small volumes (femtoliters to nanoliters) with very …

In this paper an overview is provided on practical difficulties as well as applications of
capillary electrophoresis coupled to laser induced fluorescence detection methods in the …

Enzymes are biological catalysts that play an important role in biochemical reactions
necessary for normal growth, maturation and reproduction through whole live world. Their …