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Lipids and lipid derivatives for RNA delivery
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …
diseases through various mechanisms including knockdown of pathological genes …
Wearable sensors: modalities, challenges, and prospects
Wearable sensors have recently seen a large increase in both research and
commercialization. However, success in wearable sensors has been a mix of both progress …
commercialization. However, success in wearable sensors has been a mix of both progress …
Pulsed field ablation for the treatment of atrial fibrillation: PULSED AF pivotal trial
Background: Pulsed field ablation uses electrical pulses to cause nonthermal irreversible
electroporation and induce cardiac cell death. Pulsed field ablation may have effectiveness …
electroporation and induce cardiac cell death. Pulsed field ablation may have effectiveness …
Membrane electroporation and electropermeabilization: mechanisms and models
Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient
increase in their plasma membrane permeability, allowing transmembrane transport of …
increase in their plasma membrane permeability, allowing transmembrane transport of …
Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
High-voltage electrical pulses in oncology: irreversible electroporation, electrochemotherapy, gene electrotransfer, electrofusion, and electroimmunotherapy
B Geboers, HJ Scheffer, PM Graybill, AH Ruarus… - Radiology, 2020 - pubs.rsna.org
This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …
oncology to treat solid tumors with irreversible electroporation (IRE) and …
A comprehensive review of small interfering RNAs (siRNAs): mechanism, therapeutic targets, and delivery strategies for cancer therapy
J Zhang, B Chen, C Gan, H Sun, J Zhang… - International journal of …, 2023 - Taylor & Francis
Small interfering RNA (siRNA) delivery by nanocarriers has been identified as a promising
strategy in the study and treatment of cancer. Short nucleotide sequences are synthesized …
strategy in the study and treatment of cancer. Short nucleotide sequences are synthesized …
Soft bioelectronics for therapeutics
Soft bioelectronics play an increasingly crucial role in high-precision therapeutics due to
their softness, biocompatibility, clinical accuracy, long-term stability, and patient-friendliness …
their softness, biocompatibility, clinical accuracy, long-term stability, and patient-friendliness …
Recent advancements in electroporation technologies: from bench to clinic
Over the past decade, the increased adoption of electroporation-based technologies has led
to an expansion of clinical research initiatives. Electroporation has been utilized in …
to an expansion of clinical research initiatives. Electroporation has been utilized in …
Electroporation-based applications in biotechnology
Electroporation is already an established technique in several areas of medicine, but many
of its biotechnological applications have only started to emerge; we review here some of the …
of its biotechnological applications have only started to emerge; we review here some of the …