Since its discovery in 1912, 1 the Claisen rearrangement has become one of the most
widely used synthetic tools for the organic chemist. For synthetic purposes, the Claisen …

This brief review article describes developments in the aza-Claisen rearrangement over the
last nine years. In this article, the emphasis has been given to the various aspects of the aza …

In a systematic study, 21 ring-substituted benzaldehydes were reacted with glycine under
catalysis with a l-threonine aldolase (lTA) from Pseudomonas putida and a d-threonine …

Two variations of the Overman rearrangement have been developed for the highly selective
synthesis of anti-vicinal amino alcohol natural products. A MOM ether-directed palladium (II) …

Proteasome inhibition is a topic of great interest in anticancer research. The proteolytic
activity of this multicatalytic complex relies on three subunits, β1, β2 and β5, containing a …

Abstract β-Hydroxy-α-amino acids (βH-AAs) are key components of many bioactive
molecules as well as exist as specialised metabolites. Among these βH-AAs, 4 …

A copper-catalyzed nucleophilic displacement of α-triflyloxy nitriles and esters with silicon
nucleophiles allows for the stereospecific generation of highly enantioenriched α-silylated …

A rhodium-catalyzed asymmetric hydrogenation of challenging tetrasubstituted β-acetoxy-α-
enamido esters was developed, giving chiral β-acetoxy-α-amido esters in high yields with …

Several new synthetic methods to diverse polycycles and heterocycles on the basis of [3, 3]‐
sigmatropic rearrangement and ring‐closing metathesis as key steps are summarized. In …

A new approach for the stereoselective synthesis of the piperidine alkaloid (+)-α-conhydrine
and its pyrrolidine derivative has been developed using a palladium (II)-catalyzed, MOM …