Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly
SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …
Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma
The unique cancer-associated immunosuppression in brain, combined with a paucity of
infiltrating T cells, contributes to the low response rate and poor treatment outcomes of T cell …
infiltrating T cells, contributes to the low response rate and poor treatment outcomes of T cell …
Supramolecular filament hydrogel as a universal immunomodulator carrier for immunotherapy combinations
A major challenge of cancer immunotherapy is to develop delivery strategies that can
effectively and safely augment the immune system's antitumor response. Here, we report on …
effectively and safely augment the immune system's antitumor response. Here, we report on …
Recent trends in the development of hydrogel therapeutics for the treatment of central nervous system disorders
Q Li, X Shao, X Dai, Q Guo, B Yuan, Y Liu… - NPG Asia …, 2022 - nature.com
The central nervous system (CNS) controls the acquisition and processing of peripheral
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …
Therapeutic supramolecular polymers: Designs and applications
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …
has unlocked a new realm of materials with distinct properties and tremendous potential for …
Vitamin C supramolecular hydrogel for enhanced cancer immunotherapy
H Zhang, K Liu, Y Gong, W Zhu, J Zhu, F Pan, Y Chao… - Biomaterials, 2022 - Elsevier
Vitamin C (VitC) has shown great promise to promote cancer immunotherapy, however, its
high hydrophilicity makes it quickly excreted, leading to limited therapeutic efficiency even …
high hydrophilicity makes it quickly excreted, leading to limited therapeutic efficiency even …
Activation of TRPV1 by capsaicin-loaded CaCO3 nanoparticle for tumor-specific therapy
Capsaicin is a natural non-toxic small molecular organic substance, which is often used
clinically to reduce inflammation and pain. Here, we report an acid-responsive CaCO 3 …
clinically to reduce inflammation and pain. Here, we report an acid-responsive CaCO 3 …
Collagen-binding peptide-enabled supramolecular hydrogel design for improved organ adhesion and sprayable therapeutic delivery
Spraying serves as an attractive, minimally invasive means of administering hydrogels for
localized delivery, particularly due to high-throughput deposition of therapeutic depots over …
localized delivery, particularly due to high-throughput deposition of therapeutic depots over …
Intramitochondrial disulfide polymerization controls cancer cell fate
S Kim, B Jana, EM Go, JE Lee, S **, EK An, J Hwang… - ACS …, 2021 - ACS Publications
Recent advances in supramolecular chemistry research have led to the development of
artificial chemical systems that can form self-assembled structures that imitate proteins …
artificial chemical systems that can form self-assembled structures that imitate proteins …