Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma

F Wang, Q Huang, H Su, M Sun… - Proceedings of the …, 2023 - National Acad Sciences
The unique cancer-associated immunosuppression in brain, combined with a paucity of
infiltrating T cells, contributes to the low response rate and poor treatment outcomes of T cell …

Supramolecular filament hydrogel as a universal immunomodulator carrier for immunotherapy combinations

F Wang, H Su, Z Wang, CF Anderson, X Sun, H Wang… - ACS …, 2023 - ACS Publications
A major challenge of cancer immunotherapy is to develop delivery strategies that can
effectively and safely augment the immune system's antitumor response. Here, we report on …

Recent trends in the development of hydrogel therapeutics for the treatment of central nervous system disorders

Q Li, X Shao, X Dai, Q Guo, B Yuan, Y Liu… - NPG Asia …, 2022 - nature.com
The central nervous system (CNS) controls the acquisition and processing of peripheral
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …

Therapeutic supramolecular polymers: Designs and applications

H Wang, J Mills, B Sun, H Cui - Progress in polymer science, 2024 - Elsevier
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …

Vitamin C supramolecular hydrogel for enhanced cancer immunotherapy

H Zhang, K Liu, Y Gong, W Zhu, J Zhu, F Pan, Y Chao… - Biomaterials, 2022 - Elsevier
Vitamin C (VitC) has shown great promise to promote cancer immunotherapy, however, its
high hydrophilicity makes it quickly excreted, leading to limited therapeutic efficiency even …

Activation of TRPV1 by capsaicin-loaded CaCO3 nanoparticle for tumor-specific therapy

M Xu, J Zhang, Y Mu, MF Foda, H Han - Biomaterials, 2022 - Elsevier
Capsaicin is a natural non-toxic small molecular organic substance, which is often used
clinically to reduce inflammation and pain. Here, we report an acid-responsive CaCO 3 …

Collagen-binding peptide-enabled supramolecular hydrogel design for improved organ adhesion and sprayable therapeutic delivery

CF Anderson, RW Chakroun, ME Grimmett… - Nano …, 2022 - ACS Publications
Spraying serves as an attractive, minimally invasive means of administering hydrogels for
localized delivery, particularly due to high-throughput deposition of therapeutic depots over …

Intramitochondrial disulfide polymerization controls cancer cell fate

S Kim, B Jana, EM Go, JE Lee, S **, EK An, J Hwang… - ACS …, 2021 - ACS Publications
Recent advances in supramolecular chemistry research have led to the development of
artificial chemical systems that can form self-assembled structures that imitate proteins …