The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
Current and emerging Legionella diagnostics for laboratory and outbreak investigations
JW Mercante, JM Winchell - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Legionnaires' disease (LD) is an often severe and potentially fatal form of bacterial
pneumonia caused by an extensive list of Legionella species. These ubiquitous freshwater …
pneumonia caused by an extensive list of Legionella species. These ubiquitous freshwater …
Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages
Generalist and specialist species differ in the breadth of their ecological niches. Little is
known about the niche width of obligate human pathogens. Here we analyzed a global …
known about the niche width of obligate human pathogens. Here we analyzed a global …
Evolutionary history and global spread of the Mycobacterium tuberculosis Bei**g lineage
Mycobacterium tuberculosis strains of the Bei**g lineage are globally distributed and are
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia …
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia …
A robust SNP barcode for ty** Mycobacterium tuberculosis complex strains
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an
important factor in pathogenesis that may affect virulence, transmissibility, host response …
important factor in pathogenesis that may affect virulence, transmissibility, host response …
Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
LJ Pankhurst, C del Ojo Elias, AA Votintseva… - The Lancet …, 2016 - thelancet.com
Background Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …
Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance
Multidrug-resistant tuberculosis (MDR-TB), caused by drug-resistant strains of
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …
Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs
Background Mycobacterium tuberculosis resistance to anti-tuberculosis drugs is a major
threat to global public health. Whole genome sequencing (WGS) is rapidly gaining traction …
threat to global public health. Whole genome sequencing (WGS) is rapidly gaining traction …
Dissemination of Cephalosporin Resistance Genes between Escherichia coli Strains from Farm Animals and Humans by Specific Plasmid Lineages
Third-generation cephalosporins are a class of β-lactam antibiotics that are often used for
the treatment of human infections caused by Gram-negative bacteria, especially Escherichia …
the treatment of human infections caused by Gram-negative bacteria, especially Escherichia …
Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study
J van Ingen, TA Kohl, K Kranzer, B Hasse… - The Lancet Infectious …, 2017 - thelancet.com
Background Since 2013, over 100 cases of Mycobacterium chimaera prosthetic valve
endocarditis and disseminated disease were notified in Europe and the USA, linked to …
endocarditis and disseminated disease were notified in Europe and the USA, linked to …