Progress of microfluidic hydrogel‐based scaffolds and organ‐on‐chips for the cartilage tissue engineering

H Tolabi, N Davari, M Khajehmohammadi… - Advanced …, 2023 - Wiley Online Library
Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

Deconstructing the third dimension–how 3D culture microenvironments alter cellular cues

BM Baker, CS Chen - Journal of cell science, 2012 - journals.biologists.com
Much of our understanding of the biological mechanisms that underlie cellular functions,
such as migration, differentiation and force-sensing has been garnered from studying cells …

Microfluidic tissue engineering and bio‐actuation

M Filippi, T Buchner, O Yasa, S Weirich… - Advanced …, 2022 - Wiley Online Library
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …

Bioprinting methods for fabricating in vitro tubular blood vessel models

SJ Kim, MG Kim, J Kim, JS Jeon, J Park… - Cyborg and Bionic …, 2023 - spj.science.org
Dysfunctional blood vessels are implicated in various diseases, including cardiovascular
diseases, neurodegenerative diseases, and cancer. Several studies have attempted to …

Design of pressure-driven microfluidic networks using electric circuit analogy

KW Oh, K Lee, B Ahn, EP Furlani - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …

Engineered organoids for biomedical applications

NR de Barros, C Wang, S Maity, A Peirsman… - Advanced drug delivery …, 2023 - Elsevier
As miniaturized and simplified stem cell-derived 3D organ-like structures, organoids are
rapidly emerging as powerful tools for biomedical applications. With their potential for …

A low permeability microfluidic blood-brain barrier platform with direct contact between perfusable vascular network and astrocytes

S Bang, SR Lee, J Ko, K Son, D Tahk, J Ahn, C Im… - Scientific reports, 2017 - nature.com
A novel three dimensional blood brain barrier (BBB) platform was developed by
independently supplying different types of media to separate cell types within a single …

Chemoresistance of cancer cells: requirements of tumor microenvironment-mimicking in vitro models in anti-cancer drug development

Y Jo, N Choi, K Kim, HJ Koo, J Choi, HN Kim - Theranostics, 2018 - pmc.ncbi.nlm.nih.gov
For decades, scientists have been using two-dimensional cell culture platforms for high-
throughput drug screening of anticancer drugs. Growing evidence indicates that the results …

Top-down models in biology: explanation and control of complex living systems above the molecular level

G Pezzulo, M Levin - Journal of The Royal Society …, 2016 - royalsocietypublishing.org
It is widely assumed in developmental biology and bioengineering that optimal
understanding and control of complex living systems follows from models of molecular …

Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery

GT Vladisavljević, N Khalid, MA Neves… - Advanced drug delivery …, 2013 - Elsevier
Microfluidics is an emerging and promising interdisciplinary technology which offers
powerful platforms for precise production of novel functional materials (eg, emulsion …