Nonribosomal peptide synthesis—principles and prospects
RD Süssmuth, A Mainz - Angewandte Chemie International …, 2017 - Wiley Online Library
Nonribosomal peptide synthetases (NRPSs) are large multienzyme machineries that
assemble numerous peptides with large structural and functional diversity. These peptides …
assemble numerous peptides with large structural and functional diversity. These peptides …
Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis
Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide
natural products is strongly influenced by how they are released from their biosynthetic …
natural products is strongly influenced by how they are released from their biosynthetic …
The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life
Covering: up to 2013 Although holo-acyl carrier protein synthase, AcpS, a
phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until …
phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until …
Salicylic acid biosynthesis and metabolism: a divergent pathway for plants and bacteria
Salicylic acid (SA) is an active secondary metabolite that occurs in bacteria, fungi, and
plants. SA and its derivatives (collectively called salicylates) are synthesized from …
plants. SA and its derivatives (collectively called salicylates) are synthesized from …
Antimicrobial secondary metabolites from agriculturally important bacteria as next-generation pesticides
The whole organisms can be packaged as biopesticides, but secondary metabolites
secreted by microorganisms can also have a wide range of biological activities that either …
secreted by microorganisms can also have a wide range of biological activities that either …
Bioactive natural products from novel microbial sources
VL Challinor, HB Bode - Annals of the New York Academy of …, 2015 - Wiley Online Library
Despite the importance of microbial natural products for human health, only a few bacterial
genera have been mined for the new natural products needed to overcome the urgent threat …
genera have been mined for the new natural products needed to overcome the urgent threat …
Polyamine-containing natural products: structure, bioactivity, and biosynthesis
Q Long, W Zhou, H Zhou, Y Tang, W Chen… - Natural Product …, 2024 - pubs.rsc.org
Covering: 2005 to August, 2023 Polyamine-containing natural products (NPs) have been
isolated from a wide range of terrestrial and marine organisms and most of them exhibit …
isolated from a wide range of terrestrial and marine organisms and most of them exhibit …
Chemical language and warfare of bacterial natural products in bacteria–nematode–insect interactions
YM Shi, HB Bode - Natural product reports, 2018 - pubs.rsc.org
Covering: up to November 2017 Organismic interaction is one of the fundamental principles
for survival in any ecosystem. Today, numerous examples show the interaction between …
for survival in any ecosystem. Today, numerous examples show the interaction between …
Beyond peptide bond formation: the versatile role of condensation domains in natural product biosynthesis
S Dekimpe, J Masschelein - Natural product reports, 2021 - pubs.rsc.org
Covering: up to the end of 2020 Nonribosomal peptide synthetases are remarkable
molecular machines that produce a wide range of structurally complex peptide natural …
molecular machines that produce a wide range of structurally complex peptide natural …
Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights
Covering: up to 2017 The overwhelming majority of antibiotics in clinical use originate from
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …